Pure and Applied Chemistry, 2012, Volume 84, No. 7

2012, Vol. 84, Issue 7

Special topic article
23rd International Conference on Heterocyclic Chemistry (ICHC-23), Glasgow, UK, 31 July–4 August 2011
IUPAC Technical Reports and Recommendations

Special topic article

Analogue-based drug discovery: Contributions to medicinal chemistry principles and drug design strategies. Microtubule stabilizers as a case in point (Special Topic Article)

Mohammad H. El-Dakdouki and Paul W. Erhardt

p. 1479 [Details + Abstract] [Full text - pdf 2873 kB]

23rd International Conference on Heterocyclic Chemistry (ICHC-23), Glasgow, UK, 31 July–4 August 2011

This conference is part of the Heterocyclic Chemistry series.

Preface

Colin Gibson

p. iv [Details] [Full text - pdf 76 kB]

Targeting neurodegenerative diseases: Drug discovery in a challenging arena

Magid Abou-Gharbia and Wayne Childers

p. 1543 [Details + Abstract] [Full text - pdf 1331 kB]

An acyl-Claisen approach to the synthesis of lignans and substituted pyrroles

David Barker, Benjamin Dickson, Nora Dittrich and Claire E. Rye

p. 1557 [Details + Abstract] [Full text - pdf 665 kB]

Spiroketals: Toward the synthesis of 39‑oxobistramide K

Malgorzata Commandeur, Claude Commandeur and Janine Cossy

p. 1567 [Details + Abstract] [Full text - pdf 793 kB]

Designer chiral phase-transfer catalysts for green sustainable chemistry

Keiji Maruoka

p. 1575 [Details + Abstract] [Full text - pdf 721 kB]

Influence of the difluoromethylene group (CF₂) on the conformation and properties of selected organic compounds

David O'Hagan, Yi Wang, Maciej Skibinski and Alexandra M. Z. Slawin

p. 1587 [Details + Abstract] [Full text - pdf 574 kB]

Stereoselective construction of 5,11‑methanomorphanthridine and 5,10b‑phenanthridine structural frameworks: Total syntheses of (±)-pancracine, (±)‑brunsvigine, (±)-maritidine, and (±)-crinine

Ganesh Pandey and Smita R. Gadre

p. 1597 [Details + Abstract] [Full text - pdf 2384 kB]

New strategies for natural products containing chroman spiroketals

Jason C. Green, G. Leslie Burnett, IV and Thomas R. R. Pettus

p. 1621 [Details + Abstract] [Full text - pdf 951 kB]

Radical azidation reactions and their application in the synthesis of alkaloids

Guillaume Lapointe, Ajoy Kapat, Karin Weidner and Philippe Renaud

p. 1633 [Details + Abstract] [Full text - pdf 525 kB]

Total synthesis of gelsemoxonine

Jun Shimokawa, Takaaki Harada, Satoshi Yokoshima and Tohru Fukuyama

p. 1643 [Details + Abstract] [Full text - pdf 648 kB]

Chiral 2,6-bis(5',5'-diphenyloxazoline)pyridine as an efficient ligand for asymmetric catalysis