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Pure Appl. Chem., 2011, Vol. 83, No. 9, pp. 1709-1719

Published online 2011-03-29

Increased understanding of platinum anticancer chemistry

Jan Reedijk1,2

1 Department of Chemistry, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia
2 Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA, Leiden, The Netherlands

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  • Selimović Enisa, Vulović Tatjana, Petrović Biljana, Bugarčić Živadin D., Bogojeski Jovana: Complex formation reactions of two sterically hindered platinum(II) complexes with some N-bonding ligands. Transition Met Chem 2013, 38, 635. <>
  • Würtenberger Irene, Angermaier Bernhard, Kircher Brigitte, Gust Ronald: Synthesis and In Vitro Pharmacological Behavior of Platinum(II) Complexes Containing 1,2-Diamino-1-(4-fluorophenyl)-2-alkanol Ligands. J. Med. Chem. 2013, 56, 7951. <>
  • Wang Hanlu, DeYonker Nathan J., Zhang Xiting, Zhao Cunyuan, Ji Liangnian, Mao Zong-Wan: Photodissociation of a ruthenium(II) arene complex and its subsequent interactions with biomolecules: a density functional theory study. J Mol Model 2012, 18, 4675. <>
  • Wang Hanlu, DeYonker Nathan J., Gao Hui, Ji Liangnian, Zhao Cunyuan, Mao Zong-Wan: Mechanism of aquation and nucleobase binding of ruthenium (II) and osmium (II) arene complexes: A systematic comparison DFT study. J Organomet Chem 2012, 704, 17. <>
  • Reedijk Jan: Fast and slow versus strong and weak metal–DNA binding: consequences for anti-cancer activity. Metallomics 2012, 4, 628. <>
  • Casini Angela, Reedijk Jan: Interactions of anticancer Pt compounds with proteins: an overlooked topic in medicinal inorganic chemistry?. Chem. Sci. 2012, 3, 3135. <>