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Pure Appl. Chem., 2010, Vol. 82, No. 7, pp. 1429-1441

Published online 2010-05-04

Developing chiral phosphorus ligands for asymmetric hydrogenations

Wei Li, Guohua Hou, Xianfeng Sun, Gao Shang, Weicheng Zhang and Xumu Zhang*

Department of Chemistry and Chemical Biology and Department of Pharmaceutical Chemistry, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA

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  • Cong Xuefeng, Tang Huarong, Wu Chao, Zeng Xiaoming: Role of Mono-N-protected Amino Acid Ligands in Palladium(II)-Catalyzed Dehydrogenative Heck Reactions of Electron-Deficient (Hetero)arenes: Experimental and Computational Studies. Organometallics 2013, 32, 6565. <>
  • Etayo Pablo, Vidal-Ferran Anton: Rhodium-catalysed asymmetric hydrogenation as a valuable synthetic tool for the preparation of chiral drugs. Chem. Soc. Rev. 2013, 42, 728. <>
  • de Miranda Amanda S., Miranda Leandro S. M., de Souza Rodrigo O. M. A.: Ethyl acetate as an acyl donor in the continuous flow kinetic resolution of (±)-1-phenylethylamine catalyzed by lipases. Org. Biomol. Chem. 2013, 11, 3332. <>
  • Núñez-Rico José L., Etayo Pablo, Fernández-Pérez Héctor, Vidal-Ferran Anton: Modular POP Ligands in Rhodium-Mediated Asymmetric Hydrogenation: A Comparative Catalysis Study. Adv. Synth. Catal. 2012, 354, 3025. <>
  • Yu Zhengkun, Jin Weiwei, Jiang Quanbin: Brønsted-Säure-Aktivierung bei der übergangsmetallkatalysierten asymmetrischen Hydrierung N-ungeschützter Imine, Enamine und N-Heteroarene. Angew. Chem. 2012, 124, 6164. <>
  • Yu Zhengkun, Jin Weiwei, Jiang Quanbin: Brønsted Acid Activation Strategy in Transition-Metal Catalyzed Asymmetric Hydrogenation of N-Unprotected Imines, Enamines, and N-Heteroaromatic Compounds. Angew. Chem. Int. Ed. 2012, 51, 6060. <>
  • Moberg Viktor, Duquesne Robin, Contaldi Simone, Röhrs Oliver, Nachtigall Jonny, Damoense Llewellyn, Hutton Alan T., Green Michael, Monari Magda, Santelia Daniela, Haukka Matti, Nordlander Ebbe: Efficient Cluster-Based Catalysts for Asymmetric Hydrogenation of α-Unsaturated Carboxylic Acids. Chem. Eur. J. 2012, 18, 12458. <>
  • Boyd Derek R., Bell Mark, Dunne Katherine S., Kelly Brian, Stevenson Paul J., Malone John F., Allen Christopher C. R.: Chemoenzymatic synthesis of a mixed phosphine–phosphine oxide catalyst and its application to asymmetric allylation of aldehydes and hydrogenation of alkenes. Biomol Chem 2012, 10, 1388. <>
  • Lühr Susan, Holz Jens, Börner Armin: The Synthesis of Chiral Phosphorus Ligands for use in Homogeneous Metal Catalysis. ChemCatChem 2011, 3, 1708. <>
  • Li Wei, Hou Guohua, Sun Xianfeng, Shang Gao, Zhang Weicheng, Zhang Xumu: ChemInform Abstract: Developing Chiral Phosphorus Ligands for Asymmetric Hydrogenations. ChemInform 2011, 42, no. <>