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Pure Appl. Chem., 2008, Vol. 80, No. 8, pp. 1703-1718

Oxidation-responsiveness of nanomaterials for targeting inflammatory reactions

Vitaliy V. Khutoryanskiy1 and Nicola Tirelli2

1 School of Pharmacy, University of Reading, Whiteknights, Reading RG6 6AD, UK
2 School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK

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  • d'Arcy Richard, Tirelli Nicola: Fishing for fire: strategies for biological targeting and criteria for material design in anti-inflammatory therapies. Polym. Adv. Technol. 2014, n/a. <>
  • Fu Xiaohui, Ma Yinan, Shen Yong, Fu Wenxin, Li Zhibo: Oxidation-Responsive OEGylated Poly-l-cysteine and Solution Properties Studies. Biomacromolecules 2014, 15, 1055. <>
  • Maity Suman Kumar, Bera Santu, Paikar Arpita, Pramanik Apurba, Haldar Debasish: Fabrication of self-assembled peptidomimetic microspheres and hydrogen peroxide responsive release of nicotinamide. CrystEngComm 2014, 16, 2527. <>
  • Jeanmaire Damien, Laliturai Jureerat, Almalik Abdulaziz, Carampin Paolo, Richard d'Arcy, Lallana Enrique, Evans Robert, Winpenny Richard E. P., Tirelli Nicola: Chemical specificity in REDOX-responsive materials: the diverse effects of different Reactive Oxygen Species (ROS) on polysulfide nanoparticles. Polym. Chem. 2014, 5, 1393. <>
  • Lallana Enrique, Tirelli Nicola: Oxidation-Responsive Polymers: Which Groups to Use, How to Make Them, What to Expect From Them (Biomedical Applications). Macromol. Chem. Phys. 2013, 214, 143. <>
  • Vo Cong-Duan, Cadman Christopher J., Donno Roberto, Goos Jeroen A. C. M., Tirelli Nicola: Combination of Episulfide Ring-Opening Polymerization With ATRP for the Preparation of Amphiphilic Block Copolymers. Macromol. Rapid Commun. 2013, 34, 156. <>
  • Deshayes Stéphanie, Kasko Andrea M.: Polymeric biomaterials with engineered degradation. J. Polym. Sci. Part A: Polym. Chem. 2013, 51, 3531. <>
  • Qiao Zeng-Ying, Ji Ran, Huang Xiao-Nan, Du Fu-Sheng, Zhang Rui, Liang De-Hai, Li Zi-Chen: Polymersomes from Dual Responsive Block Copolymers: Drug Encapsulation by Heating and Acid-Triggered Release. Biomacromolecules 2013, 14, 1555. <>
  • Song Cheng-Cheng, Ji Ran, Du Fu-Sheng, Li Zi-Chen: Oxidation-Responsive Poly(amino ester)s Containing Arylboronic Ester and Self-Immolative Motif: Synthesis and Degradation Study. Macromolecules 2013, 46, 8416. <>
  • Fuhrmann Kathrin, Połomska Anna, Aeberli Carmen, Castagner Bastien, Gauthier Marc A., Leroux Jean-Christophe: Modular Design of Redox-Responsive Stabilizers for Nanocrystals. ACS Nano 2013, 7, 8243. <>
  • Carampin Paolo, Lallana Enrique, Laliturai Jureerat, Carroccio Sabrina C., Puglisi Concetto, Tirelli Nicola: Oxidant-Dependent REDOX Responsiveness of Polysulfides. Macromol. Chem. Phys. 2012, 213, 2052. <>
  • de Gracia Lux Caroline, Joshi-Barr Shivanjali, Nguyen Trung, Mahmoud Enas, Schopf Eric, Fomina Nadezda, Almutairi Adah: Biocompatible Polymeric Nanoparticles Degrade and Release Cargo in Response to Biologically Relevant Levels of Hydrogen Peroxide. J. Am. Chem. Soc. 2012, 134, 15758. <>
  • Mahmoud Enas A., Sankaranarayanan Jagadis, Morachis José M., Kim Gloria, Almutairi Adah: Inflammation Responsive Logic Gate Nanoparticles for the Delivery of Proteins. Bioconjugate Chem 2011, 22, 1416. <>
  • Irmukhametova Galiya S., Mun Grigoriy A., Khutoryanskiy Vitaliy V.: Thiolated Mucoadhesive and PEGylated Nonmucoadhesive Organosilica Nanoparticles from 3-Mercaptopropyltrimethoxysilane. Langmuir 2011, 27, 9551. <>
  • Wang Lei, Kilcher Giona, Tirelli Nicola: Avoiding Disulfides: Improvement of Initiation and End-Capping Reactions in the Synthesis of Polysulfide Block Copolymers. Macromol Chem Phys 2009, 210, 447. <>
  • Vo Cong Duan, Kilcher Giona, Tirelli Nicola: Polymers and Sulfur: what are Organic Polysulfides Good For? Preparative Strategies and Biological Applications. Macromol Rapid Commun 2009, 30, 299. <>