Pure Appl. Chem., 2006, Vol. 78, No. 2, pp. 425-434
http://dx.doi.org/10.1351/pac200678020425
Indium-catalyzed addition of carbon units to acetylenes: Development of a new C-C bond formation toward exploitation of chemical resources
Abstract:
This account deals with an overview of the development of catalytic addition reactions of carbonyl compounds to alkynes catalyzed by a variety of indium salts. The new C-C bond formation reactions provide a powerful tool for α-functionalization of carbonyl compounds, including direct α-vinylation with acetylene, regioselective α-alkenylation, and α-ynenylation that can be applied to a modular synthesis of α-arylated β-keto esters.
Keywords
alkenylation; carbometallation; carbon–carbon bond formation; carbonyl compounds; indium catalyst.