Pure Appl. Chem., 2003, Vol. 75, No. 2-3, pp. 389-393
http://dx.doi.org/10.1351/pac200375020389
Biotransformation of triptonide by cell suspension cultures of Platycodon grandiflorum
Abstract:
The biotransformation of triptonide by cell suspension cultures of Platycodon grandiflorum was investigated. After six days of incubation, five products were obtained. On the basis of chemical and spectral evidence, their structures were elucidated as epitriptolide-14-O-β-d-glucoside, 5α-hydroxytriptonide, triptolide, triptodiolide, and 2β-hydroxytriptonide, among which epitriptolide-14-O-β-d-glucoside and 5α-hydroxytriptonide are new compounds.