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Pure Appl. Chem., 2003, Vol. 75, No. 2-3, pp. 231-234

Total synthesis of (­)-clavukerin A

E. L. Grimm, J.-L. Methot and M. Shamji

Merck Frosst Centre for Therapeutic Research, P.O.Box 1005, Pointe Claire-Dorval, Québec, H9R 4P8 Canada

Abstract: (−)-Clavukerin A has been synthesized via intramolecular Julia coupling and intramolecular sulfone ester cyclization starting from (+)-limonene oxide.