Pure Appl. Chem., 2002, Vol. 74, No. 1, pp. 129-133
http://dx.doi.org/10.1351/pac200274010129
Nickel-catalyzed cyclizations of alkynyl enones and alkynyl enals
Abstract:
Substrates that possess an a,b-unsaturated carbonyl tethered to an alkyne have been utilized in a variety of nickel-catalyzed processes. Depending on ligand structure, reagent structure, reaction conditions, and workup conditions, several different monocyclic and bicyclic ring systems may be accessed from a common substrate. Evidence for a nickel metallacycle as a common intermediate is provided.