Pure Appl. Chem., 2001, Vol. 73, No. 2, pp. 299-303
http://dx.doi.org/10.1351/pac200173020299
Recent advances in asymmetric catalysis. Synthetic applications to biologically active compounds
Abstract:
New chiral cationic ruthenium complexes have been used for the industrial synthesis of (+) -dihydrojasmonate. A new class of electron-rich C2-symmetric 2,4-disubstituted phosphetanes (CnrPHOS) was developed. Preliminary evaluation of their catalytic properties revealed high efficiency in rhodium and ruthenium-catalyzed asymmetric hydrogenations. A new stereochemical model is presented in which the phosphetane Rh-catalyzed hydrogenation follows an apparent stability-controlled mechanism.