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Pure Appl. Chem., 1987, Vol. 59, No. 3, pp. 287-294

Use of rationally designed inhibitors to study sterol and triterpenoid biosynthesis

M. Taton, P. Benveniste and A. Rahier

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  • Krojer Melanie, Müller Christoph, Bracher Franz: Steroidomimetic Aminomethyl Spiroacetals as Novel Inhibitors of the Enzyme Δ8,7-Sterol Isomerase in Cholesterol Biosynthesis. Arch. Pharm. Chem. Life Sci. 2014, 347, 108. <>
  • Burbiel Joachim, Bracher Franz: Azasteroids as antifungals. Steroid 2003, 68, 587. <>
  • Mercer E.Ian: Inhibitors of sterol biosynthesis and their applications. Lipid Res 1993, 32, 357. <>
  • Wannamaker M.Woods, Waid Philip P., Moore William R., Schatzman Gerald L., Van Sickle William A., Wilson Pamela K.: Inhibition of 2,3-oxidosqualene cyclase by N-alkylpiperidines. Biorg Med Chem Lett 1993, 3, 1175. <>
  • Huxley-Tencer Alica, Francotte Eric, Bladocha-Moreau Michelle: 1(R)-(2,6-cis-dimethylmorpholino)- 3(S)-(p-tert-butylphenyl)cyclopentane: A representative of a novel, potent class of bio-rationally designed fungicides. Pestic Sci 1992, 34, 65. <>
  • Sickle W. A., Angelastro M. R., Wilson P., Cooper J. R., Marquart A., Flanagan M. A.: Inhibition of cholesterol synthesis by cyclopropylamine derivatives of squalene in human hepatoblastoma cells in culture. Lipid 1992, 27, 157. <>
  • Mercer E. I.: Sterol biosynthesis inhibitors: Their current status and modes of action. Lipid 1991, 26, 584. <>
  • Schaller Hubert, Maillot-Vernier Pascale, Benveniste Pierre, Belliard Geneviève: Sterol composition of tobacco calli selected for resistance to fenpropimorph. Phytochemisry 1991, 30, 2547. <>
  • RAHIER Alain, TATON Maryse, BENVENISTE Pierre: Cycloeucalenol - obtusifoliol isomerase. Structural requirements for transformation or binding of substrates and inhibitors. Eur J Biochem 1989, 181, 615. <>
  • TATON Maryse, BENVENISTE Pierre, RAHIER Alain: Microsomal Delta8,14-sterol Delta14-reductase in higher plants. Characterization and inhibition by analogues of a presumptive carbocationic intermediate of the reduction reaction. Eur J Biochem 1989, 185, 605. <>
  • Taton Maryse, Benveniste Pierre, Rahier Alain: Mechanism of inhibition of sterol biosynthesis enzymes byN-substituted morpholines. Pestic. Sci. 1987, 21, 269. <>