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1987, Vol. 59, Issue 3

15th International Symposium on the Chemistry of Natural Products, Hague, The Netherlands, 17–22 August 1986

This conference is part of the Natural Products series.
Plenary lectures
Enzymic lipoxygenation of arachidonic acid: mechanism, inhibition, and role in eicosanoid biosynthesis
E. J. Corey
p. 269 [Details] [Full text - pdf 318 kB]
Crystallographic studies of the β-lactamases from B. cereus
D. C. Phillips, A. Cordero-Borboa, B. J. Sutton and R. J. Todd
p. 279 [Details] [Full text - pdf 265 kB]
Use of rationally designed inhibitors to study sterol and triterpenoid biosynthesis
M. Taton, P. Benveniste and A. Rahier
p. 287 [Details] [Full text - pdf 194 kB]
Bacterial organomercury lyase: a protonolytic detoxification catalyst
C. Walsh, Tadhg Begley and A. Walts
p. 295 [Details] [Full text - pdf 108 kB]
Progress in natural product chemistry by the chiron and related approaches - synthesis of avermectin B1a
S. Hanessian, A. Ugolini, P. J. Hodges, Pierre Beaulieu, Daniel Dube and Christiane Andre
p. 299 [Details] [Full text - pdf 458 kB]
Structure, design, and synthesis of immunoactive peptides
V. T. Ivanov, T. M. Andronova, M. V. Bezrukov, V. A. Rar, E. A. Makarov, S. A. Kozmin, M. V. Astapova, T. I. Barkova and V. A. Nesmeyanov
p. 317 [Details] [Full text - pdf 193 kB]
Developments in the chemical synthesis of naturally occurring DNA and RNA sequences with normal and unusual linkages
K. K. Ogilvie, M. J. Damha, N. Usman and R. T. Pon
p. 325 [Details] [Full text - pdf 182 kB]
Synthesis and analysis of (poly)peptides
J. W. van Nispen
p. 331 [Details] [Full text - pdf 401 kB]
Iterative butenolide construction of polypropionate chains. Application to an efficient synthesis of (+)(9S)-dihydroerythronolide A
G. Stork and S. D. Rychnovsky
p. 345 [Details] [Full text - pdf 140 kB]
Synthesis of natural products using chiral glycol precursors
S. Takano
p. 353 [Details] [Full text - pdf 266 kB]
Vitamin B12-mediated electrochemical reactions in the synthesis of natural products
R. Scheffold, Stefan Abrecht, R. Orlinski, H.-R. Ruf, P. Stamouli, O. Tinembart, L. Walder and C. Weymuth
p. 363 [Details] [Full text - pdf 235 kB]
Section lectures

Section A: Structure, chemistry and synthesis of natural products
Stereoselective synthesis of β,γ-unsaturated amino acids
Christof Angst
p. 373 [Details] [Full text - pdf 207 kB]
Generation and trapping of α-oxa and oxo o-quinodimethanes for natural product synthesis
S. V. Kessar
p. 381 [Details] [Full text - pdf 132 kB]
A synthesis of moenocinol from isoprenoid precursors
P. Welzel, Dirk Bottger, Uwe Heinz, A. Hadi Said, Andreas Fischer and Elisabeth Adams
p. 385 [Details] [Full text - pdf 365 kB]
Synthesis and uses of azetidiniminium salts
L. Ghosez, Sophie Bogdan, Marcel Ceresiat, Colin Frydrych, Jacqueline Marchand-Brynaert, M. M. Portuguez and Isabelle Huber
p. 393 [Details] [Full text - pdf 138 kB]
Synthetic studies on a stereochemically complex natural product: designs for the total synthesis of (-)-tetrodotoxin
M. Isobe, T. Nishikawa, Naoki Fukami and T. Goto
p. 399 [Details] [Full text - pdf 213 kB]
Interaction of polyamines, their protonated salts and metal complexes with nucleic acid fragments
M. D. Bratek-Wiewiorowska, M. Alejska, M. Figlerowicz, J. Barciszewski, M. Wiewiorowski, M. Jaskolski, W. Zielenkiewicz, A. Zielenkiewicz and M. Kaminski
p. 407 [Details] [Full text - pdf 237 kB]
De novo synthesis of carbohydrates and related natural products
R. R. Schmidt
p. 415 [Details] [Full text - pdf 212 kB]
Switch-functionalized systems in biomimetic chemistry
S. Shinkai
p. 425 [Details] [Full text - pdf 172 kB]
Protein crystallography, computer graphics and drug design
W. G. J. Hol
p. 431 [Details] [Full text - pdf 170 kB]
Section C: Biopolymers and their components
Chemoenzymatic synthesis of a gene for the interleukin-2 receptor
J. W. Engels, Wolfgang Becker, T. Beckers, Dieter Hüsken and W. Wetekam
p. 437 [Details] [Full text - pdf 214 kB]
Recent advances in the study of the binding site of heparin to antithrombin
P. Sinaÿ
p. 445 [Details] [Full text - pdf 95 kB]
Pierre Lefrancier and E. Lederer
p. 449 [Details] [Full text - pdf 288 kB]
Mini-symposium: Chemistry and development of new generations of β-lactams
Modification of natural products to improve their biological properties
R. N. Guthikonda, L. D. Cama, M. Quesada, M. F. Woods, T. N. Salzmann and B. G. Christensen
p. 455 [Details] [Full text - pdf 107 kB]
Structure-activity relationships of cephem analogs
M. Narisada
p. 459 [Details] [Full text - pdf 140 kB]
Penems: some recent advances
Giovanni Franceschi, Marco Alpegiani, Carlo Battistini, Angelo Bedeschi, E. Perrone and Franco Zarini
p. 467 [Details] [Full text - pdf 211 kB]
Discovery and development of new β-lactam antibiotics
A. G. Brown
p. 475 [Details] [Full text - pdf 226 kB]
Chiral control of the Staudinger reaction
R. D. G. Cooper, B. W. Daugherty and D. B. Boyd
p. 485 [Details] [Full text - pdf 266 kB]