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Pure Appl. Chem., 2013, Vol. 85, No. 2, pp. 343-354

http://dx.doi.org/10.1351/PAC-CON-12-07-08

Published online 2012-12-07

Toxicity in tumor cells, DNA binding mode, and resistance to decomposition by sulfur nucleophiles of new dinuclear bifunctional trans-PtII complexes containing long alkane linkers

Jitka Prachařová1, Olga Nováková2, Jana Kašpárková1, Dan Gibson3 and Viktor Brabec2*

1 Department of Biophysics, Faculty of Science, Palacky University, 17. listopadu 12, CZ-77146 Olomouc, Czech Republic
2 Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Kralovopolska 135, 61265 Brno, Czech Republic
3 Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem 91120, Israel

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  • Novakova Olga, Liskova Barbora, Vystrcilova Jana, Suchankova Tereza, Vrana Oldrich, Starha Pavel, Travnicek Zdenek, Brabec Viktor: Conformation and recognition of DNA damaged by antitumor cis-dichlorido platinum(II) complex of CDK inhibitor bohemine. European Journal of Medicinal Chemistry 2014, 78, 54. <http://dx.doi.org/10.1016/j.ejmech.2014.03.041>