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Pure Appl. Chem., 2012, Vol. 84, No. 11, pp. 2325-2337

http://dx.doi.org/10.1351/PAC-CON-11-11-03

Published online 2012-05-18

Identification of heat shock protein 60 as the regulator of the hypoxia-inducible factor subunit HIF-1α

Hyun Seung Ban, Kazuki Shimizu, Hidemitsu Minegishi and Hiroyuki Nakamura*

Department of Chemistry, Faculty of Science, Gakushuin University, Mejiro, Tokyo 171-8588, Japan

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  • Nakamura Hiroyuki, Tasaki Lisa, Kanoh Daisuke, Sato Shinichi, Ban Hyun Seung: Diaryl-substituted ortho-carboranes as a new class of hypoxia inducible factor-1α inhibitors. Dalton Trans. 2014, 43, 4941. <http://dx.doi.org/10.1039/c3dt52828f>
  • Cappello Francesco, Marino Gammazza Antonella, Palumbo Piccionello Antonio, Campanella Claudia, Pace Andrea, Conway de Macario Everly, Macario Alberto JL: Hsp60 chaperonopathies and chaperonotherapy: targets and agents. Expert Opin. Ther. Targets 2014, 18, 185. <http://dx.doi.org/10.1517/14728222.2014.856417>
  • Minegishi Hidemitsu, Matsukawa Takuya, Nakamura Hiroyuki: Synthesis and Biological Evaluation of Diaryl-Substituted Carboranes as Inhibitors of Hypoxia Inducible Factor (HIF)-1 Transcriptional Activity. ChemMedChem 2013, 8, 265. <http://dx.doi.org/10.1002/cmdc.201200502>
  • Nakamura Hiroyuki, Yasui Yuka, Ban Hyun Seung: Synthesis and biological evaluation of ortho-carborane containing benzoxazole as an inhibitor of hypoxia inducible factor (HIF)-1 transcriptional activity. Journal of Organometallic Chemistry 2013, 747, 189. <http://dx.doi.org/10.1016/j.jorganchem.2013.04.007>