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Pure Appl. Chem., 2011, Vol. 83, No. 3, pp. 607-612

http://dx.doi.org/10.1351/PAC-CON-10-09-15

Published online 2011-01-31

Oxidative decarboxylation of α-amino acids to nitriles using o-iodoxybenzoic acid in aqueous ammonia

Eknath V. Bellale, Sameerana N. Huddar, Ulhas S. Mahajan and Krishnacharya G. Akamanchi*

Department of Pharmaceutical Sciences & Technology, Institute of Chemical Technology, Matunga, Mumbai 400 019, India

Abstract: Formation of the nitrile was the outcome of the investigation of biochemically significant oxidative decarboxylation of amino acids using o-iodoxybenzoic acid (IBX) in aqueous ammonia system.