Enantioselective reactions catalyzed by chiral pyridine 2,6-bis(5',5'-diphenyloxazoline)-metal complexes

Singh, Pradeep K.; Singh, Vinod K.

doi:10.1351/PAC-CON-09-09-40

Pure Appl. Chem., 2010, Vol. 82, No. 9, pp. 1845-1853

http://dx.doi.org/10.1351/PAC-CON-09-09-40

Published online 2010-05-30

Enantioselective reactions catalyzed by chiral pyridine 2,6-bis(5',5'-diphenyloxazoline)-metal complexes

Pradeep K. Singh¹ and Vinod K. Singh^1,2*

¹ Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, India
² Indian Institute of Science Education and Research, ITI Campus (Gas Rahat) Building, Govindpura, Bhopal 460 023, India

Abstract: A new class of tridentate pyridine-bis(oxazoline) ligand having gem-diphenyl groups at C5 of the oxazoline rings has been developed. Its metal complex exhibited high catalytic efficiency in asymmetric synthesis. We have shown that gem-diphenyl groups at C5 of the oxazoline rings are essential for getting high enantiomeric excess.