Pure Appl. Chem., 2010, Vol. 82, No. 9, pp. 1827-1833
http://dx.doi.org/10.1351/PAC-CON-09-12-12
Published online 2010-06-28
Copper-catalyzed enantioselective aziridination of styrenes
Abstract:
Studies regarding the copper-catalyzed enantioselective aziridination of styrenes with N-tosyloxycarbamates are presented. Catalyst, ligand, and reagent optimization will be discussed. Chiral aziridines were obtained in good yields and modest-to-good levels of stereochemical induction.