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Pure Appl. Chem., 2010, Vol. 82, No. 9, pp. 1735-1748

Published online 2010-06-04

Lessons from the total synthesis of (±)‑phalarine: Insights into the mechanism of the Pictet–Spengler reaction

John D. Trzupek1, Chaomin Li2, Collin Chan2, Brendan M. Crowley1, Annekatrin C. Heimann1 and Samuel J. Danishefsky2,1*

1 Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10065, USA
2 Department of Chemistry, Columbia University, Havemeyer Hall, 3000 Broadway, New York, NY 10027, USA

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