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Pure Appl. Chem., 2010, Vol. 82, No. 8, pp. 1599-1607

http://dx.doi.org/10.1351/PAC-CON-09-10-42

Published online 2010-05-13

Factors influencing hairpin oligonucleotide cyclization by the uncatalyzed alkyne-azide cycloaddition (AAC) reaction

Afaf H. El-Sagheer1,2 and Tom Brown2*

1 Chemistry Branch, Department of Science and Mathematics, Faculty of Petroleum and Mining Engineering, Suez Canal University, Suez, Egypt
2 School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK

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  • El-Sagheer Afaf H., Brown Tom: Click Nucleic Acid Ligation: Applications in Biology and Nanotechnology. Acc. Chem. Res. 2012, 45, 1258. <http://dx.doi.org/10.1021/ar200321n>
  • El-Sagheer Afaf H., Cheong Vee Vee, Brown Tom: Rapid chemical ligation of oligonucleotides by the Diels–Alder reaction. Org Biomol Chem 2011, 9, 232. <http://dx.doi.org/10.1039/c0ob00451k>
  • Shelbourne Montserrat, Chen Xiong, Brown Tom, El-Sagheer Afaf H.: Fast copper-free click DNA ligation by the ring-strain promoted alkyne-azide cycloaddition reaction. Chem Commun 2011, 47, 6257. <http://dx.doi.org/10.1039/c1cc10743g>