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Pure Appl. Chem., 2010, Vol. 82, No. 2, pp. 493-504

Published online 2010-01-04

Metallomics: Guidelines for terminology and critical evaluation of analytical chemistry approaches (IUPAC Technical Report)

Ryszard Lobinski1,2*, J. Sabine Becker3, Hiroki Haraguchi4 and Bibundhendra Sarkar5

1 CNRS/UPPA, UMR5254, Laboratory of Analytical, Bio-Inorganic, and Environmental Chemistry, Hélioparc, 2, av. Pr. Angot, 64053 Pau, France
2 Department of Chemistry, Warsaw University of Technology, ul. Noakowskiego 3, 00-664 Warszawa, Poland
3 Central Division of Analytical Chemistry, Research Centre Jülich, D-52425 Jülich, Germany
4 Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan
5 The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada

Abstract: Definitions for the terms "metallome" and "metallomics" are proposed. The state of the art of analytical techniques and methods for systematic studies of metal content, speciation, localization, and use in biological systems is briefly summarized and critically evaluated.