Metallomics: Guidelines for terminology and critical evaluation of analytical chemistry approaches (IUPAC Technical Report)

Lobinski, Ryszard; Becker, J. Sabine; Haraguchi, Hiroki; Sarkar, Bibundhendra

doi:10.1351/PAC-REP-09-03-04

Pure Appl. Chem., 2010, Vol. 82, No. 2, pp. 493-504

http://dx.doi.org/10.1351/PAC-REP-09-03-04

Published online 2010-01-04

Metallomics: Guidelines for terminology and critical evaluation of analytical chemistry approaches (IUPAC Technical Report)

Ryszard Lobinski^1,2*, J. Sabine Becker³, Hiroki Haraguchi⁴ and Bibundhendra Sarkar⁵

¹ CNRS/UPPA, UMR5254, Laboratory of Analytical, Bio-Inorganic, and Environmental Chemistry, Hélioparc, 2, av. Pr. Angot, 64053 Pau, France
² Department of Chemistry, Warsaw University of Technology, ul. Noakowskiego 3, 00-664 Warszawa, Poland
³ Central Division of Analytical Chemistry, Research Centre Jülich, D-52425 Jülich, Germany
⁴ Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan
⁵ The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada

Abstract: Definitions for the terms "metallome" and "metallomics" are proposed. The state of the art of analytical techniques and methods for systematic studies of metal content, speciation, localization, and use in biological systems is briefly summarized and critically evaluated.