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Pure Appl. Chem., 2010, Vol. 82, No. 12, pp. 2231-2246

http://dx.doi.org/10.1351/PAC-CON-10-08-04

Published online 2010-10-04

Recent advances in the total synthesis of agelastatins*

Guangbin Dong

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA

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  • Yoshimitsu Takehiko: Endeavors to Access Molecular Complexity: Strategic Use of Free Radicals in Natural Product Synthesis. The Chemical Record 2014, n/a. <http://dx.doi.org/10.1002/tcr.201300024>
  • Kim Cheol-Eui, Park Sangjune, Eom Dahan, Seo Boram, Lee Phil Ho: Synthesis of Pyrroles from Terminal Alkynes, N-Sulfonyl Azides, and Alkenyl Alkyl Ethers through 1-Sulfonyl-1,2,3-triazoles. Org. Lett. 2014, 16, 1900. <http://dx.doi.org/10.1021/ol500718s>
  • Duspara Petar A., Batey Robert A.: A Short Total Synthesis of the Marine Sponge Pyrrole-2-aminoimidazole Alkaloid (±)-Agelastatin A. Angew. Chem. 2013, 125, 11062. <http://dx.doi.org/10.1002/ange.201304759>
  • Duspara Petar A., Batey Robert A.: A Short Total Synthesis of the Marine Sponge Pyrrole-2-aminoimidazole Alkaloid (±)-Agelastatin A. Angew. Chem. Int. Ed. 2013, 52, 10862. <http://dx.doi.org/10.1002/anie.201304759>
  • Fukahori Yusuke, Takayama Yohei, Imaoka Takuya, Iwamoto Osamu, Nagasawa Kazuo: Intramolecular 1,3-Dipolar Cycloaddition-Mediated Stereoselective Synthesis of Disubstituted Cyclopentane: A Simple Model for the Cyclopentane Ring System of Polycyclic Oroidine Alkaloids. Chem. Asian J. 2013, 8, 244. <http://dx.doi.org/10.1002/asia.201200820>
  • Han Sunkyu, Siegel Dustin S., Morrison Karen C., Hergenrother Paul J., Movassaghi Mohammad: Synthesis and Anticancer Activity of All Known (−)-Agelastatin Alkaloids. J. Org. Chem. 2013, 78, 11970. <http://dx.doi.org/10.1021/jo4020112>
  • Bharathiraja Ganesan, Sakthivel Sekarpandi, Sengoden Mani, Punniyamurthy Tharmalingam: A Novel Tandem Sequence to Pyrrole Syntheses by 5-endo-dig Cyclization of 1,3-Enynes with Amines. Org. Lett. 2013, 15, 4996. <http://dx.doi.org/10.1021/ol402305b>
  • Li Zhimin, Shigeoka Daisuke, Caulfield Thomas R., Kawachi Takashi, Qiu Yushi, Kamon Takuma, Arai Masayoshi, Tun Han W., Yoshimitsu Takehiko: An integrated approach to the discovery of potent agelastatin A analogues for brain tumors: chemical synthesis and biological, physicochemical and CNS pharmacokinetic analyses. Med. Chem. Commun. 2013, 4, 1093. <http://dx.doi.org/10.1039/c3md00094j>
  • Morris Jonathan C.: Marine natural products: synthetic aspects. Nat. Prod. Rep. 2013, 30, 783. <http://dx.doi.org/10.1039/c3np20116c>
  • Reyes Jeremy Chris P., Romo Daniel: Bioinspired Total Synthesis of Agelastatin A. Angew. Chem. 2012, 124, 6976. <http://dx.doi.org/10.1002/ange.201200959>
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  • Dong Guangbin: ChemInform Abstract: Recent Advances in the Total Synthesis of Agelastatins. ChemInform 2011, 42, no. <http://dx.doi.org/10.1002/chin.201136217>
  • Menjo Yasuhiro, Hamajima Akinari, Sasaki Neri, Hamada Yasumasa: Asymmetric Aziridination of Cyclic Enones Using Chiral Diamine Catalysts and Its Application to the Total Synthesis of (−)-Agelastatin A. Org Lett 2011, 13, 5744. <http://dx.doi.org/10.1021/ol2023054>