Pure Appl. Chem., 2008, Vol. 80, No. 5, pp. 881-890
http://dx.doi.org/10.1351/pac200880050881
New methods in asymmetric catalysis based on new hemi-labile bidentate ligands
Abstract:
Chiral bidentate hemi-labile bis(phosphine) monoxide ligands were shown to be quite effective in various copper-catalyzed transformations. Among them, the nucleophilic addition to imines, the conjugate addition to α,β-unsaturated nitro derivatives, and the conjugate reduction of α,β-unsaturated sulfones generally gave good to excellent yields and high enantiomeric excesses.
Keywords
bis(phosphine) monoxide; chiral amines; conjugate addition; hemi-labile bidentate ligands; organozinc.