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Pure Appl. Chem., 2007, Vol. 79, No. 12, pp. 2339-2349

Screening of acetylcholinesterase inhibitors in snake venom by electrospray mass spectrometry*

André Liesener1, Anna-Maria Perchuc2, Reto Schöni2, Nils Helge Schebb3, Marianne Wilmer2 and Uwe Karst1,3

1 University of Twente, Chemical Analysis Group and MESA+ Institute for Nanotechnology, P.O. Box 217, 7500 AE Enschede, The Netherlands
2 Pentapharm Ltd., Engelgasse 109, 4002 Basel, Switzerland
3 Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstrasse 30, 48149 Münster, Germany

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  • Zhang Bing, Ni Boli, Lü Shaoyu, Cui Dapeng, Liu Mingzhu, Gong Honghong, Han Fei: Synthesis and characterization of a novel potato starch derivative with cationic acetylcholine groups. International Journal of Biological Macromolecules 2012, 50, 701. <>
  • Holas Ondrej, Musilek Kamil, Pohanka Miroslav, Kuca Kamil: The progress in the cholinesterase quantification methods. Expert Opin. Drug Discov. 2012, 7, 1207. <>
  • Schebb Nils Helge, Huby Marion, Morisseau Christophe, Hwang Sung Hee, Hammock Bruce D.: Development of an online SPE–LC–MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors. Anal Bioanal Chem 2011, 400, 1359. <>
  • Siemerink Mathijs, Schebb Nils Helge, Liesener André, Perchuc Anna-Maria, Schöni Reto, Wilmer Marianne, Hayen Heiko, Karst Uwe, Vogel Martin: Development of a fast liquid chromatography/mass spectrometry screening method for angiotensin-converting enzyme (ACE) inhibitors in complex natural mixtures like snake venom. Rapid Commun Mass Spectrom 2010, 24, 687. <>
  • Current literature in mass spectrometry. J Mass Spectrom 2008, 43, 827. <>