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Pure Appl. Chem., 2007, Vol. 79, No. 1, pp. 39-54

http://dx.doi.org/10.1351/pac200779010039

Amide-based molecular shuttles (2001-2006)*

José Berná, Giovanni Bottari, David A. Leigh and Emilio M. Pérez

School of Chemistry, University of Edinburgh, The King's Buildings, West Mains Road, Edinburgh EH9 3JJ, UK

Abstract: Stimuli-responsive molecular shuttles are rotaxanes in which the macrocycle can be translocated from one position on the thread to a second site in response to an external trigger. Here, we present a brief overview of the contributions of the Leigh group to the field from 2001 to 2006. In this short period of time, molecular shuttles have moved from little more than laboratory curiosities to truly functional molecular machines.
*Pure Appl. Chem. 79, 1-65 (2007). A collection of invited, peer-reviewed articles by the winners of the 2006 IUPAC Prize for Young Chemists.