Pure Appl. Chem., 2006, Vol. 78, No. 7, pp. 1369-1375
http://dx.doi.org/10.1351/pac200678071369
Iridium-catalyzed borylation of arenes and heteroarenes via C-H activation
Abstract:
Direct C-H borylation of aromatic compounds catalyzed by a transition-metal complex was studied as an economical protocol for the synthesis of aromatic boron derivatives. Iridium complexes generated from Ir(I) precursors and 2,2'-bipyridine ligands efficiently catalyzed the reactions of arenes and heteroarenes with bis(pinacolato)diboron or pinacolborane to produce a variety of aryl- and heteroarylboron compounds. The catalytic cycle involves the formation of a tris(boryl)iridium(III) species and its oxidative addition to an aromatic C-H bond.
Keywords
arylboron compounds; bis(pinacolato)diboron; C–H activation; iridium catalyst; pinacolborane.