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Pure Appl. Chem., 2006, Vol. 78, No. 5, pp. 993-1002

Enhanced P-stereodependent stability of complexes formed by phosphorothioate oligonucleotides due to involvement of sulfur as strong hydrogen bond acceptor

Piotr Guga, Małgorzata Boczkowska, Magdalena Janicka, Anna Maciaszek, Barbara Nawrot, Sławomir Antoszczyk and Wojciech J. Stec

Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Department of Bioorganic Chemistry, Sienkiewicza 112, 90-363 Lódź, Poland

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  • Gao Yang, McLuckey Scott A.: Electron transfer followed by collision-induced dissociation (NET-CID) for generating sequence information from backbone-modified oligonucleotide anions. Rapid Commun. Mass Spectrom. 2013, 27, 249. <>
  • Moriguchi Tomohisa, Sekine Mitsuaki, Shinozuka Kazuo: Novel method of the synthesis and hybridization properties of an oligonucleotide containing non-ionic diisopropylsilyl internucleotide linkage. Bioorganic & Medicinal Chemistry 2013, 21, 8013. <>
  • Guga Piotr, Koziołkiewicz Maria: Phosphorothioate Nucleotides and Oligonucleotides - Recent Progress in Synthesis and Application. C&B 2011, 8, 1642. <>
  • Oka Natsuhisa, Wada Takeshi: Stereocontrolled synthesis of oligonucleotide analogs containing chiral internucleotidic phosphorus atoms. Chemical Society Review 2011, 40, 5829. <>
  • Knobloch Bernd, Nawrot Barbara, Okruszek Andrzej, Sigel Roland K. O.: Discrimination in Metal-Ion Binding to RNA Dinucleotides with a Non-Bridging Oxygen or Sulfur in the Phosphate Diester Link. Chem Eur J 2008, 14, 3100. <>
  • Nuzzi Andrea, Massi Alessandro, Dondoni Alessandro: Model Studies Toward the Synthesis of Thymidine Oligonucleotides with Triazole Internucleosidic LinkagesVia Iterative Cu(I)-Promoted Azide–Alkyne Ligation Chemistry. QSAR Comb Sci 2007, 26, 1191. <>