Pure Appl. Chem., 2006, Vol. 78, No. 2, pp. 351-361
http://dx.doi.org/10.1351/pac200678020351
Palladium-catalyzed ring-forming reactions: Methods and applications
Abstract:
Several Pd-catalyzed cyclization methods were developed, including norbornene-mediated Catellani-type reactions, a Pd-catalyzed coupling reaction of aryl iodides and allyl moieties, and a tandem C-N/C-C coupling of gem-dihalovinyl systems. These ring-forming methods were applied to the synthesis of highly functionalized carbocyclic and heterocyclic compounds. Intermolecular Pd-catalyzed methods for synthesis of highly substituted arene compounds were also developed.
Keywords
coupling; cyclization; direct arylation; heterocycles; indole; palladium; tandem reactions.