Pure Appl. Chem., 2006, Vol. 78, No. 10, pp. 1857-1866
http://dx.doi.org/10.1351/pac200678101857
Synthesis of fine chemicals by the conjugate addition of nitroalkanes to electrophilic alkenes
Abstract:
Several aliphatic nitro compounds have been employed as stabilized carbanions in the conjugate addition to a variety of electron-poor alkenes (Michael reaction). Depending on the nature of the alkene, new carbon-carbon single or double bonds can be generated. However, all the Michael adducts can be efficiently utilized as key building blocks for the synthesis of a huge array of fine chemicals, including homo- and heterocyclic structures.
Keywords
carbon-carbon double bond; carbon-carbon single bond; fine chemicals; Michael reaction; nitroalkanes.