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Pure Appl. Chem., 2005, Vol. 77, No. 7, pp. 1183-1189

http://dx.doi.org/10.1351/pac200577071183

Application of the carbene cyclization-cycloaddition cascade in total synthesis

Pauline Chiu

Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, China

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  • Lalli Claudia, Bouma Marinus J., Bonne  Damien, Masson Géraldine, Zhu Jieping: Exploiting the Divergent Reactivity of α-Isocyanoacetate: Multicomponent Synthesis of 5-Alkoxyoxazoles and Related Heterocycles. Chem Eur J 2011, 17, 880. <http://dx.doi.org/10.1002/chem.201002098>
  • Muthusamy Sengodagounder, Gangadurai Chinnakuzhanthai, Krishnamurthi Janagiraman, Suresh Eringathodi: Stereoselective synthesis of piperidinone and quinolinone systems via ring opening reactions using TiCl4/silyl reagents. Tetrahed 2011, 67, 4212. <http://dx.doi.org/10.1016/j.tet.2011.04.049>
  • Padwa Albert: Intramolecular cycloaddition of carbonyl ylides as a strategy for natural product synthesis. Tetrahed 2011, 67, 8057. <http://dx.doi.org/10.1016/j.tet.2011.07.009>
  • Xing Siyang, Pan Wenyan, Liu Chang, Ren Jun, Wang Zhongwen: Efficient Construction of Oxa- and Aza-[n.2.1] Skeletons: Lewis Acid Catalyzed Intramolecular [3+2] Cycloaddition of Cyclopropane 1,1-Diesters with Carbonyls and Imines. Angew Chem 2010, 122, 3283. <http://dx.doi.org/10.1002/ange.201000563>
  • Xing Siyang, Pan Wenyan, Liu Chang, Ren Jun, Wang Zhongwen: Efficient Construction of Oxa- and Aza-[n.2.1] Skeletons: Lewis Acid Catalyzed Intramolecular [3+2] Cycloaddition of Cyclopropane 1,1-Diesters with Carbonyls and Imines. Angew Chem Int Ed 2010, 49, 3215. <http://dx.doi.org/10.1002/anie.201000563>
  • Chiu Pauline, Leung Lai To, Ko Ben C. B.: Pseudolaric acids: isolation, bioactivity and synthetic studies. Nat Prod Rep 2010, 27, 1066. <http://dx.doi.org/10.1039/b906520m>
  • Hong Xuechuan, France Stefan, Padwa Albert: A dipolar cycloaddition approach toward the kopsifoline alkaloid framework. Tetrahedron 2007, 63, 5962. <http://dx.doi.org/10.1016/j.tet.2007.01.064>
  • Geng Zhe, Chen Bin, Chiu Pauline: Total Synthesis of Pseudolaric Acid A. Angew Chem 2006, 118, 6343. <http://dx.doi.org/10.1002/ange.200602056>
  • Geng Zhe, Chen Bin, Chiu Pauline: Total Synthesis of Pseudolaric Acid A. Angew Chem Int Ed 2006, 45, 6197. <http://dx.doi.org/10.1002/anie.200602056>
  • Chiu Pauline: Application of the Carbene Cyclization—Cycloaddition Cascade in Total Synthesis. ChemInform 2005, 36. <http://dx.doi.org/10.1002/chin.200550265>