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Pure Appl. Chem., 2005, Vol. 77, No. 7, pp. 1183-1189

Application of the carbene cyclization-cycloaddition cascade in total synthesis

Pauline Chiu

Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, China

Abstract: The title reaction is a key transformation that has been applied to the synthetic studies of the antitumor and antifungal compounds, the pseudolaric acids.