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Pure Appl. Chem., 2005, Vol. 77, No. 12, pp. 2041-2045

http://dx.doi.org/10.1351/pac200577122041

Discovery of fused azetidines as novel selective α4β2 neuronal nicotinic receptor (NNR) agonists

Jianguo Ji, William H. Bunnelle, Tao Li, Jennifer M. Pace, Michael R. Schrimpf, Kevin B. Sippy, David J. Anderson and Michael D. Meyer

Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Dept. R47W, Bldg. AP9A, Abbott Park, IL 60064, USA

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  • Faigl Ferenc, Kovács Ervin, Turczel Gábor, Szöllősy Áron, Mordini Alessandro, Balázs László, Holczbauer Tamás, Czugler Mátyás: Novel stereoselective synthesis of 1,2,3-trisubstituted azetidines. Tetrahedron: Asymmetry 2012, 23, 1607. <http://dx.doi.org/10.1016/j.tetasy.2012.10.014>
  • Burkett Brendan A., Ting Samuel Z., Gan Gwendolyn C.S., Chai Christina L.L.: Microwave-assisted synthesis of azetidines in aqueous media. Tetrahetron Lett 2009, 50, 6590. <http://dx.doi.org/10.1016/j.tetlet.2009.09.063>
  • Napolitano Carmela, Borriello Manuela, Cardullo Francesca, Donati Daniele, Paio Alfredo, Manfredini Stefano: First synthesis of 2,6-diazabicyclo[3.2.0]heptane derivatives. Tetrahetron Lett 2009, 50, 7280. <http://dx.doi.org/10.1016/j.tetlet.2009.10.028>
  • Romanelli M. Novella, Gratteri Paola, Guandalini Luca, Martini Elisabetta, Bonaccini Claudia, Gualtieri Fulvio: Central Nicotinic Receptors: Structure, Function, Ligands, and Therapeutic Potential. ChemMedChem 2007, 2, 746. <http://dx.doi.org/10.1002/cmdc.200600207>
  • Ji Jianguo, Bunnelle William H., Li Tao, Pace Jennifer M., Schrimpf Michael R., Sippy Kevin B., Anderson David J., Meyer Michael D.: Discovery of Fused Azetidines as Novel Selective Neuronal Nicotinic Receptor (NNR) Agonists. ChemInform 2006, 37. <http://dx.doi.org/10.1002/chin.200623283>