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Pure Appl. Chem., 2003, Vol. 75, No. 2-3, pp. 209-221

http://dx.doi.org/10.1351/pac200375020209

New and old challenges in total synthesis. From concept to practice

S. Hanessian, Roberto Margarita, Adrian Hall, Shawn Johnstone, M. Tremblay and L. Parlanti

Department of Chemistry, Université de Montréal, P.O. Box 6128, Station Centre-ville, Montréal, P.Q., H3C 3J Canada

Abstract: The total synthesis of dysinosin A, a novel member of the aeruginosin group of marine natural products is discussed. The stereocontrolled synthesis also confirms the proposed structure and absolute stereochemistry of the natural product.