Pure Appl. Chem., 2003, Vol. 75, No. 2-3, pp. 179-186
http://dx.doi.org/10.1351/pac200375020179
Synthesis of carbohydrate-based antibiotics
Abstract:
Tackling the problem of carbohydrate recognition is a subject of current interest. Our strategies in this regard include development of new methods for the synthesis of saccharides and sugar arrays for screening, design of d-peptides to target bacterial cell-surface sugars, preparation of mechanism-based inhibitors of the enzymes involved in the biosynthesis of saccharides and the synthesis of aminoglycoside mimetics to target RNA.