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Pure Appl. Chem., 2003, Vol. 75, No. 2-3, pp. 167-178

Semisynthesis and degradation of the tubulin inhibitors epothilone and tubulysin

G. Höfle*, N. Glaser, T. Leibold, U. Karama, F. Sasse and H. Steinmetz

GBF, Gesellschaft für Biotechnologische Forschung mbH, Department of Natural Products, D-38124 Braunschweig, Germany

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G. Höfle, N. Glaser, T. Leibold and M. Sefkow
Epothilone A-D and their thiazole-modified analogs as novel anticancer agents
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