Pure Appl. Chem., 2003, Vol. 75, No. 11-12, pp. 2429-2432
http://dx.doi.org/10.1351/pac200375112429
Use of gene expression profiling to understand the transcriptional program associated with estrogen-induced uterine growth
Abstract:
The use of gene expression data in predictive and mechanistic toxicology is hindered by a lack of information on the relationships between transcriptional events and physiological and pathological changes. We discuss the analysis of these relationships using the rodent uterotrophic response as a model experimental system for estrogen-induced uterine growth.