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Pure Appl. Chem., 2002, Vol. 74, No. 10, pp. 1785-1792

Solubility and crystallization in biological fluids and the problems of life and health

I. Gutzow1, S. Atanassova2 and K. Neykov2

1 Institute of Physical Chemistry, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria
2 Chair of Urology, The Medical University, Sofia 1431, Bulgaria

Abstract: An analysis is given of several biologically important processes, connected with the crystallization and kinetics of liophilization in aqueous physiological solutions. These are glass formation and vitrification of life, precipitation of slightly soluble salts and kinetics of crystallization in human urine, and the solution of CaOX concretions under the influence of biocompatible solubilizators, which are normal constituents of human urine. The problems investigated experimentally are treated in the framework of the capillary theory of nucleation and the Debye–Hückel model of ionic solutions.