Pure and Applied Chemistry

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• Asad Naeem, Samarakoon Thiwanka B., Zang Qin, Loh Joanna K., Javed Salim, Hanson Paul R.: Rapid, Scalable Assembly of Stereochemically Rich, Mono- and Bicyclic Acyl Sultams. Org. Lett. 2014, 16, 82. <http://dx.doi.org/10.1021/ol403070w>
• Wender Paul A., Fournogerakis Dennis N., Jeffreys Matthew S., Quiroz Ryan V., Inagaki Fuyuhiko, Pfaffenbach Magnus: Structural complexity through multicomponent cycloaddition cascades enabled by dual-purpose, reactivity regenerating 1,2,3-triene equivalents. Nature Chem 2014. <http://dx.doi.org/10.1038/nchem.1917>
• Bhuyan Debajyoti, Sarma Rupam, Dommaraju Yuvaraj, Prajapati Dipak: Catalyst- and solvent-free, pot, atom and step economic synthesis of tetrahydroquinazolines by an aza-Diels–Alder reaction strategy. Green Chem. 2014, 16, 1158. <http://dx.doi.org/10.1039/c3gc42389a>
• Prakash G. K. Surya, Gurung Laxman, Jog Parag V., Tanaka Shinji, Thomas Tisa Elizabeth, Ganesh Nimisha, Haiges Ralf, Mathew Thomas, Olah George A.: Direct Synthesis of Diverse β-Fluoroethylamines by a Multicomponent Protocol. Chem. Eur. J. 2013, 19, 3579. <http://dx.doi.org/10.1002/chem.201204621>
• Wender Paul A.: Toward the ideal synthesis and transformative therapies: the roles of step economy and function oriented synthesis. Tetrahedron 2013, 69, 7529. <http://dx.doi.org/10.1016/j.tet.2013.06.004>
• Jiao Lei, Yu Zhi-Xiang: Vinylcyclopropane Derivatives in Transition-Metal-Catalyzed Cycloadditions for the Synthesis of Carbocyclic Compounds. J. Org. Chem. 2013, 78, 6842. <http://dx.doi.org/10.1021/jo400609w>
• Liu Jia-Yan, Li Qiu-Yun, Jiang Bo, Tu Shu-Jiang: Three-component domino reactions providing rapid and efficient routes to fully substituted pyrroles. RSC Adv. 2013, 3, 5056. <http://dx.doi.org/10.1039/c3ra40252e>
• Brady Patrick B., Albert Brian J., Akakura Matsujiro, Yamamoto Hisashi: Controlling stereochemistry in polyketide synthesis: 1,3- vs. 1,2-asymmetric induction in methyl ketone aldol additions to β-super siloxy aldehydes. Chem. Sci. 2013, 4, 3223. <http://dx.doi.org/10.1039/c3sc51183a>
• Brady Patrick B., Yamamoto Hisashi: Rapid and Stereochemically Flexible Synthesis of Polypropionates: Super-Silyl-Governed Aldol Cascades. angew chemie 2012, 124, 1978. <http://dx.doi.org/10.1002/ange.201108325>
• Fournier Jeremy, Arseniyadis Stellios, Cossy Janine: A Modular and Scalable One-Pot Synthesis of Polysubstituted Furans. Angew. Chem. 2012, 124, 7680. <http://dx.doi.org/10.1002/ange.201202486>
• Jiao Zhi-Wei, Zhang Shu-Yu, He Chuan, Tu Yong-Qiang, Wang Shao-Hua, Zhang Fu-Min, Zhang Yong-Qiang, Li Hui: Organocatalytic Asymmetric Direct C sp 3H Functionalization of Ethers: A Highly Efficient Approach to Chiral Spiroethers. Angew. Chem. 2012, 124, 8941. <http://dx.doi.org/10.1002/ange.201204274>
• Nakamura Itaru, Okamoto Masashi, Sato Yoshinori, Terada Masahiro: Synthesis of Azepine Derivatives by Rhodium-Catalyzed Tandem 2,3-Rearrangement/Heterocyclization. Angew. Chem. 2012, 124, 10974. <http://dx.doi.org/10.1002/ange.201205285>
• Brady Patrick B., Yamamoto Hisashi: Rapid and Stereochemically Flexible Synthesis of Polypropionates: Super-Silyl-Governed Aldol Cascades. Angew Chem Int E 2012, 51, 1942. <http://dx.doi.org/10.1002/anie.201108325>
• Fournier Jeremy, Arseniyadis Stellios, Cossy Janine: A Modular and Scalable One-Pot Synthesis of Polysubstituted Furans. Angew. Chem. Int. Ed. 2012, 51, 7562. <http://dx.doi.org/10.1002/anie.201202486>
• Jiao Zhi-Wei, Zhang Shu-Yu, He Chuan, Tu Yong-Qiang, Wang Shao-Hua, Zhang Fu-Min, Zhang Yong-Qiang, Li Hui: Organocatalytic Asymmetric Direct C sp 3H Functionalization of Ethers: A Highly Efficient Approach to Chiral Spiroethers. Angew. Chem. Int. Ed. 2012, 51, 8811. <http://dx.doi.org/10.1002/anie.201204274>
• Nakamura Itaru, Okamoto Masashi, Sato Yoshinori, Terada Masahiro: Synthesis of Azepine Derivatives by Rhodium-Catalyzed Tandem 2,3-Rearrangement/Heterocyclization. Angew. Chem. Int. Ed. 2012, 51, 10816. <http://dx.doi.org/10.1002/anie.201205285>
• Chen Gui-Yang, Huang Huang, Ye Jian-Liang, Wang Ai-E, Huang Hui-Ying, Zhang Hong-Kui, Huang Pei-Qiang: Enantioselective Syntheses of Rigidiusculamides A and B: Revision of the Relative Stereochemistry of Rigidiusculamide A. Chem —Asian J 2012, 7, 504. <http://dx.doi.org/10.1002/asia.201100809>
• Liao Jin-Cheng, Xiao Kai-Jiong, Zheng Xiao, Huang Pei-Qiang: A concise and divergent approach to radicamine B and hyacinthacine A3 based on a step-economic transformation. Tetrahedron 2012, 68, 5297. <http://dx.doi.org/10.1016/j.tet.2012.01.085>
• Pearson Anthony J., Zhang Sheng, Sun Huikai: Stereocontrolled Intramolecular Iron-mediated Diene/Vinyl Ether Cyclocoupling Reactions. J. Org. Chem. 2012, 77, 8835. <http://dx.doi.org/10.1021/jo301721d>
• Shapland Peter: Alkaloid synthesis: Indolizidines with ease. Nature Chem 2012, 4, 441. <http://dx.doi.org/10.1038/nchem.1364>
• Girling P. Ricardo, Batsanov Andrei S., Shen Hong C., Whiting Andrew: A multicomponent formal [1+2+1+2]-cycloaddition for the synthesis of dihydropyridines. Chem Commn 2012, 48, 4893. <http://dx.doi.org/10.1039/c2cc31495a>
• Thalluri Kishore, Nadimpally Krishna Chaitanya, Paul Ashim, Mandal Bhubaneswar: Waste reduction in amide synthesis by a continuous method based on recycling of the reaction mixture. RSC Adv. 2012, 2, 6838. <http://dx.doi.org/10.1039/c2ra20643a>
• Benedetti Erica, Simonneau Antoine, Hours Alexandra, Amouri Hani, Penoni Andrea, Palmisano Giovanni, Malacria Max, Goddard Jean-Philippe, Fensterbank Louis: (Pentamethylcyclopentadienyl)Iridium Dichloride Dimer {[IrCp*Cl2]2}: A Novel Efficient Catalyst for the Cycloisomerizations of Homopropargylic Diols and N-Tethered Enynes. Synth Catal 2011, 353, 1908. <http://dx.doi.org/10.1002/adsc.201100124>
• Li Dongzhen, Cao Yang, Shi An, Xi Zhenfeng: Facile One-Pot Construction of Polycyclic Frameworks using a Synergistic Diels-Alder Reaction, Ene Reaction, and Allylation Reaction Strategy. Chem Asian J 2011, 6, 392. <http://dx.doi.org/10.1002/asia.201000257>
• Wei Chu-Hung, Mannathan Subramaniyan, Cheng Chien-Hong: Enantioselective Synthesis of β-Substituted Cyclic Ketones via Cobalt-Catalyzed Asymmetric Reductive Coupling of Alkynes with Alkenes. J Am Chem Soc 2011, 133, 6942. <http://dx.doi.org/10.1021/ja201827j>
• Park Sangho, Volchkov Ivan, Lee Daesung: Ring Strain-Promoted Allylic Transposition of Cyclic Silyl Ethers. Org Lett 2011, 13, 3530. <http://dx.doi.org/10.1021/ol2013473>
• Tucker Joseph W., Stephenson Corey R. J.: Tandem Visible Light-Mediated Radical Cyclization–Divinylcyclopropane Rearrangement to Tricyclic Pyrrolidinones. Org Lett 2011, 13, 5468. <http://dx.doi.org/10.1021/ol202178t>
• Jiang Bo, Wang Xiang, Shi Feng, Tu Shu-Jiang, Li Guigen: New multicomponent cyclization: domino synthesis of pentasubstituted pyridines under solvent-free conditions. Org Biomol Chem 2011, 9, 4025. <http://dx.doi.org/10.1039/c0ob01258k>
• Jiang Bo, Zhang Ge, Ma Ning, Shi Feng, Tu Shu-Jiang, Kaur Parminder, Li Guigen: A new rapid multicomponent domino reaction for the formation of functionalized benzo[h]pyrazolo[3,4-b]quinolines. Org Biomol Chem 2011, 9, 3834. <http://dx.doi.org/10.1039/c1ob05034f>
• Gulías Moisés, López Fernando, Mascareñas José L.: Development of transition-metal-catalyzed cycloaddition reactions leading to polycarbocyclic systems. Pure and App Chemis 2011, 1. <http://dx.doi.org/10.1351/PAC-CON-10-10-23>
• Saito Shinichi, Maeda Kyotaro, Yamasaki Ryu, Kitamura Takuya, Nakagawa Minami, Kato Korehito, Azumaya Isao, Masu Hyuma: Synthesis of Nine-Membered Carbocycles by the [4+3+2] Cycloaddition Reaction of Ethyl Cyclopropylideneacetate and Dienynes. Angew Chem 2010, 122, 1874. <http://dx.doi.org/10.1002/ange.200907052>
• Saito Shinichi, Maeda Kyotaro, Yamasaki Ryu, Kitamura Takuya, Nakagawa Minami, Kato Korehito, Azumaya Isao, Masu Hyuma: Synthesis of Nine-Membered Carbocycles by the [4+3+2] Cycloaddition Reaction of Ethyl Cyclopropylideneacetate and Dienynes. Angew Chem Int Ed 2010, 49, 1830. <http://dx.doi.org/10.1002/anie.200907052>
• Huang Feng, Yao Zhong-Ke, Wang Yi, Wang Yuanyuan, Zhang Jialing, Yu Zhi-Xiang: RhI-Catalyzed Two-Component [(5+2)+1] Cycloaddition Approach toward [5-8-5] Ring Systems. Chem Asian J 2010, 5, 1555. <http://dx.doi.org/10.1002/asia.201000053>
• Xiao Kai-Jiong, Wang Yu, Ye Ke-Yin, Huang Pei-Qiang: Versatile One-Pot Reductive Alkylation of Lactams/Amides via Amide Activation: Application to the Concise Syntheses of Bioactive Alkaloids (±)-Bgugaine, (±)-Coniine, (+)-Preussin, and (−)-Cassine. Chem Eur J 2010, 16, 12792. <http://dx.doi.org/10.1002/chem.201002054>
• Wender Paul A., Bi F. Christopher, Gamber Gabriel G., Gosselin Francis, Hubbard Robert D., Scanio Marc J. C., Sun Robert, Williams Travis J., Zhang Lei: ChemInform Abstract: Toward the Ideal Synthesis: New Transition Metal catalyzed Reactions Inspired by Novel Medicinal Leads. ChemInform 2010, 33, no. <http://dx.doi.org/10.1002/chin.200241295>
• Croatt Mitchell P., Wender Paul A.: The Diene Effect: The Design, Development, and Mechanistic Investigation of Metal-Catalyzed Diene-yne, Diene-ene, and Diene-allene [2+2+1] Cycloaddition Reactions. Eur J Org 2010, 2010, 19. <http://dx.doi.org/10.1002/ejoc.200900929>
• Reichard Holly A., McLaughlin Martin, Chen Ming Z., Micalizio Glenn C.: Regioselective Reductive Cross-Coupling Reactions of Unsymmetrical Alkynes. Eur J Org Chem 2010, 2010, 391. <http://dx.doi.org/10.1002/ejoc.200901094>
• Wang Junfeng, Li Qin, Qi Chao, Liu Yi, Ge Zemei, Li Runtao: Primary 1,2-diamine catalysis III: an unexpected domino reaction for the synthesis of multisubstituted cyclohexa-1,3-dienamines. Org Biomol Chem 2010, 8, 4240. <http://dx.doi.org/10.1039/c0ob00089b>
• Simmons Bryon, Walji Abbas M., MacMillan David W. C.: Cycle-Specific Organocascade Catalysis: Application to Olefin Hydroamination, Hydro-oxidation, and Amino-oxidation, and to Natural Product Synthesis. Angew Chem 2009, 121, 4413. <http://dx.doi.org/10.1002/ange.200900220>
• Simmons Bryon, Walji Abbas M., MacMillan David W. C.: Cycle-Specific Organocascade Catalysis: Application to Olefin Hydroamination, Hydro-oxidation, and Amino-oxidation, and to Natural Product Synthesis. Angew Chem Int Ed 2009, 48, 4349. <http://dx.doi.org/10.1002/anie.200900220>
• Fan Xiaohui, Tang Min-Xian, Zhuo Lian-Gang, Tu Yong Qiang, Yu Zhi-Xiang: An expeditious and high-yield formal synthesis of hirsutene using Rh(I)-catalyzed [(5+2)+1] cycloaddition. Tetrahetron Lett 2009, 50, 155. <http://dx.doi.org/10.1016/j.tetlet.2008.10.023>
• Harmata Michael, Huang Chaofeng: A gold-catalyzed [4+3]-cycloaddition of functionalized dioxines. Tetrahetron Lett 2009, 50, 5701. <http://dx.doi.org/10.1016/j.tetlet.2009.07.111>
• Naganawa Yuki, Maruoka Keiji, Hashimoto Takuya: Stereoselective Construction of Seven-Membered Rings with an All-Carbon Quaternary Center by Direct Tiffeneau−Demjanov-type Ring Expansion. J Am Chem Soc 2009, 131, 6614. <http://dx.doi.org/10.1021/ja900941k>
• Jiang Bo, Tu Shu-Jiang, Kaur Parminder, Wever Walter, Li Guigen: Four-Component Domino Reaction Leading to Multifunctionalized Quinazolines. J Am Chem Soc 2009, 131, 11660. <http://dx.doi.org/10.1021/ja904011s>
• Wong Ying-Chieh, Parthasarathy Kanniyappan, Cheng Chien-Hong: Cobalt-Catalyzed Regioselective Synthesis of Pyrrolidinone Derivatives by Reductive Coupling of Nitriles and Acrylamides. J Am Chem Soc 2009, 131, 18252. <http://dx.doi.org/10.1021/ja9088296>
• Wender Paul A., Miller Benjamin L.: Synthesis at the molecular frontier. Appl Opt 2009, 460, 197. <http://dx.doi.org/10.1038/460197a>
• Sotoca Enrique, Allais Christophe, Constantieux Thierry, Rodriguez Jean: User-friendly stereoselective one-pot access to 1,4-diazepane derivatives by a cyclodehydrative three-component reaction with 1,3-dicarbonyls. Org Biomol Chem 2009, 7, 1911. <http://dx.doi.org/10.1039/b821343g>
• Hudlicky Tomas, Reed Josephine W.: Applications of biotransformations and biocatalysis to complexity generation in organic synthesis. Chem Soc Rev 2009, 38, 3117. <http://dx.doi.org/10.1039/b901172m>
• Michelet Véronique, Toullec Patrick Y., Genêt Jean-Pierre: Cycloisomerisierungen von 1,n-Eninen: faszinierende metallkatalysierte Umlagerungen und mechanistische Einblicke. Angew Chem 2008, 120, 4338. <http://dx.doi.org/10.1002/ange.200701589>
• Michelet Véronique, Toullec Patrick Y., Genêt Jean-Pierre: Cycloisomerization of 1,n-Enynes: Challenging Metal-Catalyzed Rearrangements and Mechanistic Insights. Angew Chem Int Ed 2008, 47, 4268. <http://dx.doi.org/10.1002/anie.200701589>
• Coquerel Yoann, Filippini Marie-Hélène, Bensa David, Rodriguez Jean: The MARDi Cascade: A Michael-Initiated Domino-Multicomponent Approach for the Stereoselective Synthesis of Seven-Membered Rings. Chem Eur J 2008, 14, 3078. <http://dx.doi.org/10.1002/chem.200701708>
• Shi Feng, Zhou Dianxiang, Tu Shujiang, Li Chunmei, Cao Longji, Shao Qingqing: Pot, atom and step economic synthesis of fused three heterocyclic ring compounds under microwave irradiation in water. J Heterocyclic Chem 2008, 45, 1305. <http://dx.doi.org/10.1002/jhet.5570450508>
• Lucarini Simone, Bedini Annalida, Spadoni Gilberto, Piersanti Giovanni: An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT2 melatonin receptor antagonist. Org Biomol Chem 2008, 6, 147. <http://dx.doi.org/10.1039/b713904g>
• Saito Shinichi, Maeda Kyotaro: Nickel-catalyzed [3+2+2] cycloaddition of ethyl cyclopropylideneacetate and diynes. Synthesis of 7,6- and 7,5-fused bicyclic compounds. Tetrahetron Lett 2007, 48, 3173. <http://dx.doi.org/10.1016/j.tetlet.2007.03.051>
• Clarke Paul A., Zaytzev Andrey V., Whitwood Adrian C.: Pot, atom and step economic (PASE) synthesis of highly functionalized piperidines: a five-component condensation. Tetrahetron Lett 2007, 48, 5209. <http://dx.doi.org/10.1016/j.tetlet.2007.05.141>
• Clarke Paul A., Santos Soraia, Martin William H. C.: Combining pot, atom and step economy (PASE) in organic synthesis. Synthesis of tetrahydropyran-4-ones. Green Chem 2007, 9, 438. <http://dx.doi.org/10.1039/b700923b>
• Wender Paul A., Croatt Mitchell P., Deschamps Nicole M.: Metal-Catalyzed [2+2+1] Cycloadditions of 1,3-Dienes, Allenes, and CO. Angew Chem 2006, 118, 2519. <http://dx.doi.org/10.1002/ange.200600300>
• Wender Paul A., Deschamps Nicole M., Sun Robert: RhI-Catalyzed CC Bond Activation: Seven-Membered Ring Synthesis by a [6+1] Carbonylative Ring-Expansion Reaction of Allenylcyclobutanes. Angew Chem 2006, 118, 4061. <http://dx.doi.org/10.1002/ange.200600806>
• Wender Paul A., Croatt Mitchell P., Deschamps Nicole M.: Metal-Catalyzed [2+2+1] Cycloadditions of 1,3-Dienes, Allenes, and CO. Angew Chem Int Ed 2006, 45, 2459. <http://dx.doi.org/10.1002/anie.200600300>
• Wender Paul A., Deschamps Nicole M., Sun Robert: RhI-Catalyzed CC Bond Activation: Seven-Membered Ring Synthesis by a [6+1] Carbonylative Ring-Expansion Reaction of Allenylcyclobutanes. Angew Chem Int Ed 2006, 45, 3957. <http://dx.doi.org/10.1002/anie.200600806>
• Liéby-Muller Frédéric, Simon Céline, Constantieux Thierry, Rodriguez Jean: Current Developments in Michael Addition-Based Multicomponent Domino Reactions Involving 1,3-Dicarbonyls and Derivatives. QSAR Comb Sci 2006, 25, 432. <http://dx.doi.org/10.1002/qsar.200540201>
• Wender Paul A., Croatt Mitchell P., Witulski Bernhard: New reactions and step economy: the total synthesis of (±)-salsolene oxide based on the type II transition metal-catalyzed intramolecular [4+4] cycloaddition. Tetrahedron 2006, 62, 7505. <http://dx.doi.org/10.1016/j.tet.2006.02.085>
• Trost Barry M., Shen Hong C., Horne Daniel B., Toste F. Dean, Steinmetz Bernhard G., Koradin Christopher: Syntheses of Seven-Membered Rings: Ruthenium-Catalyzed Intramolecular [5+2] Cycloadditions. Chem Eur J 2005, 11, 2577. <http://dx.doi.org/10.1002/chem.200401065>
• Ulaczyk-Lesanko Agnieszka, Hall Dennis G: Wanted: new multicomponent reactions for generating libraries of polycyclic natural products. Curr Opin Chem Biol 2005, 9, 266. <http://dx.doi.org/10.1016/j.cbpa.2005.04.003>
• Pearson Anthony J., Wang Xiaolong: Dynamic kinetic resolution during iron carbonyl promoted [6+2] ene-type reactions. Tetrahetron Lett 2005, 46, 3123. <http://dx.doi.org/10.1016/j.tetlet.2005.02.166>
• Pearson Anthony J., Wang Xiaolong: A stereospecific intramolecular [4π+4π] cycloaddition reaction between tricarbonyliron-complexed cyclohexadiene and pendant dienes. Tetrahetron Lett 2005, 46, 4809. <http://dx.doi.org/10.1016/j.tetlet.2005.05.045>
• Badham Neil F.: Homologation of ketones into carboxylic acids. Tetrahedron 2004, 60, 11. <http://dx.doi.org/10.1016/j.tet.2003.10.040>