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Pure Appl. Chem., 2001, Vol. 73, No. 9, pp. 1429-1436

http://dx.doi.org/10.1351/pac200173091429

NMR spectroscopy in drug design

Markus Heller1 and Horst Kessler1,2

1 Institut für Organische Chemie und Biochemie, Technische Universität München, Lichtenbergstrasse 4, 85747 Garching, Germany
2 Novaspin Biotech GmbH, Mühlfeldweg 46, 85748 Garching, Germany

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  • Lis-Cieplak Agnieszka, Sitkowski Jerzy, Kolodziejski Waclaw: Comparative Proton Nuclear Magnetic Resonance Studies of Amantadine Complexes Formed in Aqueous Solutions with Three Major Cyclodextrins. J. Pharm. Sci. 2014, 103, 274. <http://dx.doi.org/10.1002/jps.23802>
  • López-Cebral Rita, Martin-Pastor Manuel, Paolicelli Patrizia, Casadei Maria Antonietta, Seijo Begoña, Sanchez Alejandro: Application of NMR spectroscopy in the development of a biomimetic approach for hydrophobic drug association with physical hydrogels. Colloids and Surfaces B: Biointerfaces 2014, 115, 391. <http://dx.doi.org/10.1016/j.colsurfb.2013.12.022>
  • Sinha Sudipta K., Saiz Leonor: Determinants of protein–ligand complex formation in the thyroid hormone receptor α: a Molecular Dynamics simulation study. Computational and Theoretical Chemistry 2014. <http://dx.doi.org/10.1016/j.comptc.2014.03.034>
  • Ahmad Ejaz, Rabbani Gulam, Zaidi Nida, Khan Mohammad Azam, Qadeer Atiyatul, Ishtikhar Mohd, Singh Saurabh, Khan Rizwan Hasan: Revisiting ligand-induced conformational changes in proteins: essence, advancements, implications and future challenges. Journal of Biomolecular Structure and Dynamics 2013, 31, 630. <http://dx.doi.org/10.1080/07391102.2012.706081>
  • Hiroaki Hidekazu: Recent applications of isotopic labeling for protein NMR in drug discovery. Expert Opin. Drug Discov. 2013, 8, 523. <http://dx.doi.org/10.1517/17460441.2013.779665>
  • Klages Jochen, Coles Murray, Kessler Horst: NMR-based screening: a powerful tool in fragment-based drug discovery. Analyst 2007, 132, 692. <http://dx.doi.org/10.1039/b709658p>
  • Klages Jochen, Coles Murray, Kessler Horst: NMR-based screening: a powerful tool in fragment-based drug discovery. Mol Biosyst 2006, 2, 318. <http://dx.doi.org/10.1039/b605309m>