Pure and Applied Chemistry

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• Bhat Chinmay, Tilve Santosh G.: Recent advances in the synthesis of naturally occurring pyrrolidines, pyrrolizidines and indolizidine alkaloids using proline as a unique chiral synthon. RSC Adv. 2014, 4, 5405. <http://dx.doi.org/10.1039/c3ra44193h>
• Hu Lei, Ramström Olof: Silver-catalyzed dynamic systemic resolution of α-iminonitriles in a 1,3-dipolar cycloaddition process. Chem. Commun. 2014, 50, 3792. <http://dx.doi.org/10.1039/c4cc00944d>
• Senter Timothy J., Schulte Michael L., Konkol Leah C., Wadzinski Tyler E., Lindsley Craig W.: A general, enantioselective synthesis of 1-azabicyclo[m.n.0]alkane ring systems. Tetrahedron Letters 2013, 54, 1645. <http://dx.doi.org/10.1016/j.tetlet.2013.01.041>
• Lu Qing, Huang Xin,, Song Gonghua, Sun Chung-Ming, Jasinski Jerry P., Keeley Amanda C., Zhang Wei: Sequential [3 + 2] and [4 + 2] Cycloadditions for Stereoselective Synthesis of a Novel Polyheterocyclic Scaffold. ACS Comb. Sci. 2013, 15, 350. <http://dx.doi.org/10.1021/co400026s>
• Shu Chao, Liu Meng-Qi, Wang Shan-Shan, Li Long, Ye Long-Wu: Gold-Catalyzed Oxidative Cyclization of Chiral Homopropargyl Amides: Synthesis of Enantioenriched γ-Lactams. J. Org. Chem. 2013, 78, 3292. <http://dx.doi.org/10.1021/jo400127x>
• Fadeyi Olugbeminiyi O., Senter Timothy J., Hahn Kristopher N., Lindsley Craig W.: A Versatile Enantioselective Synthesis of Azabicyclic Ring Systems: A Concise Total Synthesis of (+)-Grandisine D and Unnatural Analogues. Chemistry A European Journal 2012, 18, 5826. <http://dx.doi.org/10.1002/chem.201200629>
• Combettes Lorraine E., Schuler Marie, Patel Rakesh, Bonillo Baltasar, Odell Barbara, Thompson Amber L., Claridge Tim D. W., Gouverneur Véronique: Synthesis of 3-Fluoropyrrolidines and 4-Fluoropyrrolidin-2-ones from Allylic Fluorides. Chem. Eur. J. 2012, 18, 13126. <http://dx.doi.org/10.1002/chem.201201576>
• Mohite Amar R., Sultane Prakash R., Bhat Ramakrishna G.: BF3·Et2O and trifluoroacetic acid/triethyl amine-mediated synthesis of functionalized piperidines. Tetrahetron Lett 2012, 53, 30. <http://dx.doi.org/10.1016/j.tetlet.2011.10.072>
• Chiou Wen-Hua, Chen Guei-Tang, Kao Chien-Lun, Gao Yu-Kai: Syntheses of (−)-pelletierine and (−)-homopipecolic acid. Biomol Chem 2012, 10, 2518. <http://dx.doi.org/10.1039/c2ob06984a>
• A. Ciufolini Marco, Dylan Turner Charles: Useful Building Blocks for the Stereocontrolled Assembly of 2,3,5-Trisubstituted Pyrrolidines. HETEROCYCLES 2012, 85, 85. <http://dx.doi.org/10.3987/COM-11-12368>
• Hsu Shih-Fan, Ko Chih-Wei, Wu Yao-Ting: Cobalt-Catalyzed Carbon-Carbon Bond Formation: Synthesis and Applications of Enantiopure Pyrrolidine Derivatives[1]. Synth Catal 2011, 353, 1756. <http://dx.doi.org/10.1002/adsc.201100220>
• Ponpandian T., Muthusubramanian S.: A new method of synthesising (±)-thalictroidine and (±)-hygrine. Tetrahedron Letters 2011, 52, 1520. <http://dx.doi.org/10.1016/j.tetlet.2011.01.132>
• Davies Stephen G., Lee James A., Roberts Paul M., Thomson James E., West Callum J.: Asymmetric synthesis of (−)-codonopsinine. Tetrahedron Letters 2011, 52, 6477. <http://dx.doi.org/10.1016/j.tetlet.2011.09.114>
• Adrio Javier, Carretero Juan C.: Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides. Chem Commun 2011, 47, 6784. <http://dx.doi.org/10.1039/c1cc10779h>
• Bisogno Fabricio R., Cuetos Aníbal, Orden Alejandro A., Kurina-Sanz Marcela, Lavandera Iván, Gotor Vicente: Chemo- and Stereodivergent Preparation of Terminal Epoxides and Bromohydrins through One-Pot Biocatalysed Reactions: Access to Enantiopure Five- and Six-Membered N-Heterocycles. Adv Synth Catal 2010, 352, 1657. <http://dx.doi.org/10.1002/adsc.201000353>
• Sammet Karsten, Gastl Christoph, Baro Angelika, Laschat Sabine, Fischer Peter, Fettig Ina: Enders’ SAMP-Hydrazone as Traceless Auxiliary in the Asymmetric 1,4-Addition of Cuprates to Enones. Synth Catal 2010, 352, 2281. <http://dx.doi.org/10.1002/adsc.201000412>
• Enders Dieter, Göddertz Dominik P., Beceño Christian, Raabe Gerhard: Asymmetric Synthesis of Polyfunctionalized Pyrrolidines via a Thiourea Catalyzed Domino Mannich/Aza-Michael Reaction. Adv Synth Catal 2010, 352, 2863. <http://dx.doi.org/10.1002/adsc.201000658>
• Lu Liang-Qiu, Zhang Ji-Ji, Li Fang, Cheng Ying, An Jing, Chen Jia-Rong, Xiao Wen-Jing: Tuning Electronic and Steric Effects: Highly Enantioselective [4+1] Pyrroline Annulation of Sulfur Ylides with α,β-Unsaturated Imines. Angew Chem 2010, 122, 4597. <http://dx.doi.org/10.1002/ange.201000755>
• Lu Liang-Qiu, Zhang Ji-Ji, Li Fang, Cheng Ying, An Jing, Chen Jia-Rong, Xiao Wen-Jing: Tuning Electronic and Steric Effects: Highly Enantioselective [4+1] Pyrroline Annulation of Sulfur Ylides with α,β-Unsaturated Imines. Angew Chem Int Ed 2010, 49, 4495. <http://dx.doi.org/10.1002/anie.201000755>
• Robles-Machín Rocío, Alonso Inés, Adrio Javier, Carretero Juan C.: Catalytic Asymmetric 1,3-Dipolar Cycloaddition of α-Iminonitriles. Chemistry - A European Journal 2010, 16, 5286. <http://dx.doi.org/10.1002/chem.200903443>
• Xiao Kai-Jiong, Wang Yu, Ye Ke-Yin, Huang Pei-Qiang: Versatile One-Pot Reductive Alkylation of Lactams/Amides via Amide Activation: Application to the Concise Syntheses of Bioactive Alkaloids (±)-Bgugaine, (±)-Coniine, (+)-Preussin, and (−)-Cassine. Chem Eur J 2010, 16, 12792. <http://dx.doi.org/10.1002/chem.201002054>
• Enders Dieter, Thiebes Christoph: ChemInform Abstract: Efficient Stereoselective Syntheses of Piperidine, Pyrrolidine, and Indolizidine Alkaloids. ChemInform 2010, 32, no. <http://dx.doi.org/10.1002/chin.200146290>
• Mo Fanyang, Li Fei, Qiu Di, Wang Jianbo: Enantioselective synthesis of condensed and transannular ring skeletons containing pyrrolidine moiety. Tetrahedron 2010, 66, 1274. <http://dx.doi.org/10.1016/j.tet.2009.12.013>
• López-Pérez Ana, Adrio Javier, Carretero Juan C.: The Phenylsulfonyl Group as a Temporal Regiochemical Controller in the Catalytic Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides. Angew Chem 2009, 121, 346. <http://dx.doi.org/10.1002/ange.200805063>
• López-Pérez Ana, Adrio Javier, Carretero Juan C.: The Phenylsulfonyl Group as a Temporal Regiochemical Controller in the Catalytic Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides. Angew Chem Int Ed 2009, 48, 340. <http://dx.doi.org/10.1002/anie.200805063>
• Bonnaventure Isabelle, Charette André B.: Stereoselective synthesis of N-heterocycles: application of the asymmetric Cu-catalyzed addition of Et2Zn to functionalized alkyl and aryl imines. Tetrahedron 2009, 65, 4968. <http://dx.doi.org/10.1016/j.tet.2009.04.002>
• Jahn Ullrich, Kafka František, Pohl Radek, Jones Peter G.: N,3,4-Trisubstituted pyrrolidines by electron transfer-induced oxidative cyclizations of N-allylic β-amino ester enolates. Tetrahedron 2009, 65, 10917. <http://dx.doi.org/10.1016/j.tet.2009.10.034>
• Ribes Celia, Falomir Eva, Murga Juan, Carda Miguel, Marco J. Alberto: Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines C, O and P. Tetrahedron 2009, 65, 10612. <http://dx.doi.org/10.1016/j.tet.2009.10.066>
• Ribes Celia, Falomir Eva, Murga Juan, Carda Miguel, Alberto Marco J.: Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines D and M. Org Biomol Chem 2009, 7, 1355. <http://dx.doi.org/10.1039/b821431j>
• Ruiz Nerea, Reyes Efraím, Vicario Jose L., Badía Dolores, Carrillo Luisa, Uria Uxue: Organocatalytic Enantioselective Synthesis of Highly Functionalized Polysubstituted Pyrrolidines. Chem Eur J 2008, 14, 9357. <http://dx.doi.org/10.1002/chem.200800788>
• Miyata Okiko, Takahashi Shinya, Tamura Akira, Ueda Masafumi, Naito Takeaki: Novel synthesis of substituted pyrrolidines and piperidines via radical addition–ionic cyclization reaction of oxime ethers. Tetrahedron 2008, 64, 1270. <http://dx.doi.org/10.1016/j.tet.2007.11.081>
• Li Hao, Zu Liansuo, Xie Hexin, Wang Jian, Wang Wei: Highly enantio- and diastereoselective organocatalytic cascade aza-Michael–Michael reactions: a direct method for the synthesis of trisubstituted chiral pyrrolidines. Chem Commun 2008, 5636. <http://dx.doi.org/10.1039/b812464g>
• Siegrist Romain, Zürcher Martina, Baumgartner Corinne, Seiler Paul, Diederich François, Daum Sebastian, Fischer Gunter, Klein Christian, Dangl Markus, Schwaiger Manfred: A Novel Synthesis of Highly Substituted Perhydropyrrolizines, Perhydroindolizines, and Pyrrolidines: Inhibition of the Peptidyl-Prolylcis/trans Isomerase (PPIase) Pin1. HCA 2007, 90, 217. <http://dx.doi.org/10.1002/hlca.200790028>
• Etxebarria Juan, Vicario Jose L., Badía Dolores, Carrillo Luisa: A general and enantiodivergent method for the asymmetric synthesis of piperidine alkaloids: concise synthesis of (R)-pipecoline, (S)-coniine and other 2-alkylpiperidines. Tetrahedron 2007, 63, 11421. <http://dx.doi.org/10.1016/j.tet.2007.08.067>
• Morita Nobuyoshi, Krause Norbert: Gold-Catalyzed Cycloisomerization of α-Aminoallenes to 3-Pyrrolines –Optimization and Mechanistic Studies. Eur J Org Chem 2006, 2006, 4634. <http://dx.doi.org/10.1002/ejoc.200600438>
• Bellur Esen, Freifeld Ilia, Böttcher Dominique, Bornscheuer Uwe T., Langer Peter: Synthesis of (tetrahydrofuran-2-yl)acetates based on a ‘cyclization/hydrogenation/enzymatic kinetic resolution’ strategy. Tetrahedron 2006, 62, 7132. <http://dx.doi.org/10.1016/j.tet.2006.03.077>
• Palacios Francisco, Aparicio Domitila, López Yago, de los Santos Jesús M.: Synthesis of functionalized α-amino-phosphine oxides and -phosphonates by addition of amines and aminoesters to 4-phosphinyl- and 4-phosphonyl-1,2-diaza-1,3-butadienes. Tetrahedron 2005, 61, 2815. <http://dx.doi.org/10.1016/j.tet.2005.01.081>
• Gebauer Julian, Dewi Purnama, Blechert Siegfried: Stereoselective synthesis of substituted N-heterocycles via sequential cross metathesis—reductive cyclization. Tetrahetron Lett 2005, 46, 43. <http://dx.doi.org/10.1016/j.tetlet.2004.11.030>
• Weintraub Philip M., Sabol Jeffrey S., Kane John M., Borcherding David R.: Recent advances in the synthesis of piperidones and piperidines. Tetrahedron 2003, 59, 2953. <http://dx.doi.org/10.1016/S0040-4020(03)00295-3>
• Kamimura Akio, Omata Yoji, Tanaka Keiichi, Shirai Masashi: Oxyoxazolidinone as an auxiliary for heterocyclic synthesis. Enantioselective formation of N-unprotected 2-pyrrolidones from selenocarboxylate and allylamines via radical cyclization. Tetrahedron 2003, 59, 6291. <http://dx.doi.org/10.1016/S0040-4020(03)01015-9>
• Ma Shengming, Jiao Ning: Pd0-Catalyzed Three-Component Tandem Double-Addition-Cyclization Reaction: Stereoselective Synthesis ofcis-Pyrrolidine Derivatives. Angew Chem 2002, 114, 4931. <http://dx.doi.org/10.1002/ange.200290032>
• Ma Shengming, Jiao Ning: Pd0-Catalyzed Three-Component Tandem Double-Addition-Cyclization Reaction: Stereoselective Synthesis ofcis-Pyrrolidine Derivatives. Angew Chem Int Ed 2002, 41, 4737. <http://dx.doi.org/10.1002/anie.200290033>
• Enders Dieter, Nolte Bert, Raabe Gerhard, Runsink Jan: Asymmetric synthesis and structural assignment of (−)-α-conhydrine. Tet Asymm 2002, 13, 285. <http://dx.doi.org/10.1016/S0957-4166(02)00066-6>
• Christoffers Jens, Mann Alexander: Enantioselektiver Aufbau quartärer Stereozentren. Angew Chem 2001, 113, 4725. <http://dx.doi.org/10.1002/1521-3757(20011217)113:24<4725::AID-ANGE4725>3.0.CO;2-L>
• Christoffers Jens, Mann Alexander: Enantioselective Construction of Quaternary Stereocenters. Angew Chem Int E 2001, 40, 4591. <http://dx.doi.org/10.1002/1521-3773(20011217)40:24<4591::AID-ANIE4591>3.0.CO;2-V>