Pure Appl. Chem., 2001, Vol. 73, No. 2, pp. 325-329
http://dx.doi.org/10.1351/pac200173020325
Asymmetric synthesis with "privileged" ligands
Abstract:
Different types of chiral "privileged" ligands 1 and 2 in promoting enantioselective addition of allylating agents to aliphatic and aromatic aldehydes are described. Here, a new concept in the asymmetric allylation reaction is presented. Redox [Cr (Salen) ] mediated addition of allyl halides to carbonyl compounds is described, and mechanistic investigations are discussed. These results open access to the fascinating area of the catalytic redox processes mediated by metallo-Salen complexes.