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Pure Appl. Chem., 2001, Vol. 73, No. 1, pp. 175-180

Applications of green chemistry in the manufacture of oligonucleotide drugs

Yogesh S. Sanghvi, V. T. Ravikumar, Anthony N. Scozzari and Douglas L. Cole

Development Chemistry and Pharmaceutics, Isis Pharmaceuticals, Inc., 2292 Faraday Avenue, Carlsbad, CA 92008, USA

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  • Sanghvi Yogesh S., Ravikumar V. T., Scozzari Anthony N., Cole Douglas L.: ChemInform Abstract: Applications of Green Chemistry in the Manufacture of Oligonucleotide Drugs. ChemInform 2010, 32, no. <>
  • Krishna Kumar R., Ravikumar Vasulinga T.: 4,4′-Dimethoxytrityl group derived from secondary alcohols: Are they removed slowly under acidic conditions?. Biorg Med Chem Lett 2005, 15, 3426. <>
  • Ranasinghe Rohan T., Brown Tom: Fluorescence based strategies for genetic analysis. Chem Commun 2005, 5487. <>
  • Tripathi Snehlata, Misra Krishna, Sanghvi Yogesh S.: FLUOROUS SILYL PROTECTING GROUP FOR 5'-HYDROXYL PROTECTION OF OLIGONUCLEOSIDES. Org Prep Proced Int 2005, 37, 257. <>
  • Uzagare Matthew C., Sanghvi Yogesh S., Salunkhe M. M.: Efficient DMTMM Promoted Nucleoside Loading of CPG Solid Support for Oligonucleotide Synthesis. Synth Common 2004, 34, 1071. <>
  • Garcı́a Javier, Fernández Susana, Ferrero Miguel, Sanghvi Yogesh S., Gotor Vicente: Novel enzymatic synthesis of levulinyl protected nucleosides useful for solution phase synthesis of oligonucleotides. Tet Asymm 2003, 14, 3533. <>
  • Uzagare Matthew C., Padiya Kamlesh J., Salunkhe Manikrao M., Sanghvi Yogesh S.: NBS–DMSO as a nonaqueous nonbasic oxidation reagent for the synthesis of oligonucleotides. Biorg Med Chem Lett 2003, 13, 3537. <>