Pure Appl. Chem., 2000, Vol. 72, No. 9, pp. 1635-1639
http://dx.doi.org/10.1351/pac200072091635
Synthetic studies toward pyranonaphthoquinone antibiotics
Abstract:
A furofuran annulation/oxidative rearrangement strategy was used to construct the basic skeleton of the pyranonaphthoquinone family of antibiotics. This synthetic methodology has been applied to the synthesis of the spiroacetal-containing pyranonaphthoquinone antibiotic griseusin A, to an analog of the C-glycoside medermycin, and to a dimeric pyranonaphthoquinone.