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Pure Appl. Chem., 2000, Vol. 72, No. 12, pp. 2343-2358

Dendrimers as reactive modules for the synthesis of new structure-controlled, higher-complexity megamers

Donald A. Tomalia*, Srinivas Uppuluri, Douglas R. Swanson and Jing Li

Center for Biologic Nanotechnology, University of Michigan, 4027 Kresge Research Bldg. II, 200 Zina Pitcher Place, Ann Arbor, MI 48109, USA

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  • Laznickova A., Biricova V., Laznicek M., Hermann P.: Mono(pyridine-N-oxide) DOTA analog and its G1/G4-PAMAM dendrimer conjugates labeled with 177Lu: Radiolabeling and biodistribution studies. Applied Radiation and Isotopes 2014, 84, 70. <>
  • Wang Yanlan, Salmon Lionel, Ruiz Jaime, Astruc Didier: Metallodendrimers in three oxidation states with electronically interacting metals and stabilization of size-selected gold nanoparticles. Nat Comms 2014, 5. <>
  • van Dongen Mallory A., Vaidyanathan S., Banaszak Holl Mark M.: PAMAM dendrimers as quantized building blocks for novel nanostructures. Soft Matter 2013, 9, 11188. <>
  • Hu Jingjing, Xu Tongwen, Cheng Yiyun: NMR Insights into Dendrimer-Based Host–Guest Systems. Chem. Rev. 2012, 112, 3856. <>
  • Kozaki Masatoshi, Morita Shirou, Suzuki Shuichi, Okada Keiji: Construction of Snowflake-Shaped Dendritic Covalent Assemblies with Rigid Conjugated Networks. J. Org. Chem. 2012, 77, 9447. <>
  • Roncaglia Diana I., Carballido-Landeira Jorge, Muñuzuri Alberto P.: Pattern formation in the Belousov–Zhabotinsky-PAMAM dendrimer system. Phys Chem Chem Phys 2011, 13, 7426. <>
  • Tomalia Donald A.: Dendrons/dendrimers: quantized, nano-element like building blocks for soft-soft and soft-hard nano-compound synthesis. Soft Matt 2010, 6, 456. <>
  • Pettirossi Stefania, Bellachioma Gianfranco, Ciancaleoni Gianluca, Zuccaccia Cristiano, Zuccaccia Daniele, Macchioni Alceo: Diffusion and NOE NMR Studies on Multicationic DAB-Organoruthenium Dendrimers: Size-Dependent Noncovalent Self-Assembly to Megamers and Ion Pairing. Chem Eur J 2009, 15, 5337. <>
  • Tomalia Donald A.: In quest of a systematic framework for unifying and defining nanoscience. J Nanopart Res 2009, 11, 1251. <>
  • Khan Mohamed K., Minc Leah D., Nigavekar Shraddha S., Kariapper Muhammed S.T., Nair Bindu M., Schipper Matthew, Cook Andrew C., Lesniak Wojciech G., Balogh Lajos P.: Fabrication of {198Au0} radioactive composite nanodevices and their use for nanobrachytherapy. Nanomed Nanotechnol 2008, 4, 57. <>
  • Newkome George R., Shreiner Carol D.: Poly(amidoamine), polypropylenimine, and related dendrimers and dendrons possessing different 1→2 branching motifs: An overview of the divergent procedures. Polymer 2008, 49, 1. <>
  • Cason Chevelle A., Oehrle Stuart A., Fabré Thomas A., Girten Craig D., Walters Keith A., Tomalia Donald A., Haik Kristi L., Bullen Heather A.: Improved Methodology for Monitoring Poly(amidoamine) Dendrimers Surface Transformations and Product Quality by Ultra Performance Liquid Chromatography. Journal of Nanomaterials 2008, 2008, 1. <>
  • Cutler Erin C., Lundin Erik, Garabato B. Davis, Choi Daeock, Shon Young-Seok: Dendritic functionalization of monolayer-protected gold nanoparticles. Mat Res Bul 2007, 42, 1178. <>
  • de Queiroz Alvaro Antonio Alencar, Abraham Gustavo Abel, Camillo Maria Aparecida Pires, Higa Olga Zazuco, Silva Gerald Saraiva, Fernández María Del Mar, Román Julio San: Physicochemical and antimicrobial properties of boron-complexed polyglycerol–chitosan dendrimers. Journal of Biomaterials Science, Polymer Edition 2006, 17, 689. <>
  • Khopade Ajay J., Möhwald Helmuth: Statistical Megamer Morphologies and Materials from PAMAM Dendrimers. Macromol Rapid Commun 2005, 26, 445. <>
  • Marcos Mercedes, Martín-Rapún Rafael, Serrano José-Luis, Sánchez-Ferrer Antoni: Liquid Crystalline Dendritic Networks Derived from Poly(propylene imine) (PPI) Dendrimers. Macromol Rapid Commun 2005, 26, 1604. <>
  • Smith David K., Hirst Andrew R., Love Christine S., Hardy John G., Brignell Sonia V., Huang Buqing: Self-assembly using dendritic building blocks—towards controllable nanomaterials. Prog Polym Sci 2005, 30, 220. <>
  • Tomalia Donald A.: Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry. Prog Polym Sci 2005, 30, 294. <>
  • Tomalia Donald A.: The dendritic state. Mat Today 2005, 8, 34. <>
  • Morgan Meredith T., Carnahan Michael A., Finkelstein Stella, Prata Carla A. H., Degoricija Lovorka, Lee Stephen J., Grinstaff Mark W.: Dendritic supramolecular assemblies for drug delivery. Chem Commun 2005, 4309. <>
  • Tomalia Donald A., Fréchet Jean M. J.: Discovery of dendrimers and dendritic polymers: A brief historical perspective. J Polym Sci A Polym Chem 2002, 40, 2719. <>
  • Urata Kouichi, Takaishi Naotake: Self-assembly of compounds based on a glycerin skeleton as a C-3 building block. Part I. J Surfact Deterg 2002, 5, 287. <>
  • Urata Kouichi, Takaishi Naotake: Self-assembly of compounds based on a glycerin skeleton as C-3 building block. Part II. J Surfact Deterg 2002, 5, 403. <>
  • Balzani Vincenzo, Ceroni Paola, Gestermann Sven, Gorka Marius, Kauffmann Christopher, Vögtle Fritz: Fluorescent guests hosted in fluorescent dendrimers. Tetrahedron 2002, 58, 629. <>