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Pure Appl. Chem., 1994, Vol. 66, No. 4, pp. 837-844

Design, synthesis, and evaluation of DNA minor groove binding agents: the duocarmycins

D. L. Boger

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  • Tanasova Marina, Sturla Shana J.: Chemistry and Biology of Acylfulvenes: Sesquiterpene-Derived Antitumor Agents. Chem. Rev. 2012, 112, 3578. <>
  • Okajima Toshiya, Shirakawa Yoko, Hashikawa Akane: On the reaction of mutagenic aflatoxin B1 oxide and benz[a]pyrene diol oxide with guanine residue in DNA double helix. Journal of Molecular Structure: THEOCHEM 2002, 581, 157. <>
  • Gupta Rajesh, Kapur Amit, Beck Jennifer L., Sheil Margaret M.: Positive ion electrospray ionization mass spectrometry of double-stranded DNA/drug complexes. Rapid Commun Mass Spectrom 2001, 15, 2472. <>
  • Boger Dale L, Han Nianhe: CC-1065/duocarmycin and bleomycin A2 hybrid agents: Lack of enhancement of DNA alkylation by attachment to noncomplementary DNA binding subunits. biorg med chem 1997, 5, 233. <>
  • Boger Dale L., Johnson Douglas S.: CC-1065 und die Duocarmycine: mechanistische Studien zum Verständnis ihrer biologischen Funktion. Angew Chem 1996, 108, 1542. <>
  • Boger Dale L., Nishi Takahide: Diastereoselective Dieckmann condensation suitable for introduction of the duocarmycin A C6 center: Development of a divergent strategy for the total synthesis of duocarmycins A and SA. biorg med chem 1995, 3, 67. <>
  • Boger Dale L., Yun Weiya, Han Nianhe, Johnson Douglas S.: CC-1065 CBI analogs: an example of enhancement of DNA alkylation efficiency through introduction of stabilizing electrostatic interactions. Bioorganic & Medicinal Chemistry 1995, 3, 611. <>
  • Boger Dale L., Yun Weiya, Cai Hui, Han Nianhe: CBI-CDPBO1 and CBI-CDPBI1: CC-1065 analogs containing deep-seated modifications in the DNA binding subunit. Bioorganic & Medicinal Chemistry 1995, 3, 761. <>
  • Boger Dale L., Yun Weiya, Han Nianhe: 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation. biorg med chem 1995, 3, 1429. <>