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Pure Appl. Chem., 1990, Vol. 62, No. 7, pp. 1449-1452

Baker's yeast mediated synthesis of natural products

C. Fuganti

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  • Brenna Elisabetta, Gatti Francesco G., Monti Daniela, Parmeggiani Fabio, Serra Stefano: Stereochemical Outcome of the Biocatalysed Reduction of Activated Tetrasubstituted Olefins by Old Yellow Enzymes 1-3. Adv. Synth. Catal. 2012, 354, 105. <>
  • Goretti Marta, Branda Eva, Turchetti Benedetta, Cramarossa Maria Rita, Onofri Andrea, Forti Luca, Buzzini Pietro: Response surface methodology as optimization strategy for asymmetric bioreduction of (4S)-(+)-carvone by Cryptococcus gastricus. Bioresource Technology 2012, 121, 290. <>
  • Brenna Elisabetta, Fronza Giovanni, Fuganti Claudio, Gatti Francesco G., Manfredi Alessia, Parmeggiani Fabio, Ronchi Paolo: On the stereochemistry of the Baker's Yeast-mediated reduction of regioisomeric unsaturated aldehydes: Examples of enantioselectivity switch promoted by substrate-engineering. Journal of Molecular Catalysis B: Enzymatic 2012, 84, 94. <>
  • Brenna Elisabetta, Gatti Francesco G., Manfredi Alessia, Monti Daniela, Parmeggiani Fabio: Enoate Reductase-Mediated Preparation of Methyl (S)-2-Bromobutanoate, a Useful Key Intermediate for the Synthesis of Chiral Active Pharmaceutical Ingredients. Org Process Res Devel 2012, 16, 262. <>
  • Tauber Katharina, Hall Melanie, Kroutil Wolfgang, Fabian Walter M.F., Faber Kurt, Glueck Silvia M.: A highly efficient ADH-coupled NADH-recycling system for the asymmetric bioreduction of carbon-carbon double bonds using enoate reductases. Biotechnol. Bioeng. 2011, 108, 1462. <>
  • Brenna Elisabetta, Gatti Francesco G., Manfredi Alessia, Monti Daniela, Parmeggiani Fabio: Biocatalyzed Enantioselective Reduction of Activated C=C Bonds: Synthesis of Enantiomerically Enriched α-Halo-β-arylpropionic Acids. Eur J Org Chem 2011, 2011, 4015. <>
  • Richter Nina, Gröger Harald, Hummel Werner: Asymmetric reduction of activated alkenes using an enoate reductase from Gluconobacter oxydans . Appl Microbiol Biotechnol 2011, 89, 79. <>
  • Brenna Elisabetta, Fronza Giovanni, Fuganti Claudio, Monti Daniela, Parmeggiani Fabio: Enantioselective CC bond reduction of unsaturated α-chloro esters by old yellow enzymes. Mol Catal B Enzym 2011. <>
  • Mueller Nicole J., Stueckler Clemens, Hauer Bernhard, Baudendistel Nina, Housden Hazel, Bruce Neil C., Faber Kurt: The Substrate Spectra of Pentaerythritol Tetranitrate Reductase, Morphinone Reductase, N-Ethylmaleimide Reductase and Estrogen-Binding Protein in the Asymmetric Bioreduction of Activated Alkenes. Adv Synth Catal 2010, 352, 387. <>
  • Hall Mélanie, Stueckler Clemens, Ehammer Heidemarie, Pointner Eva, Oberdorfer Gustav, Gruber Karl, Hauer Bernard, Stuermer Rainer, Kroutil Wolfgang, Macheroux Peter: Asymmetric Bioreduction of CC Bonds using Enoate Reductases OPR1, OPR3 and YqjM: Enzyme-Based Stereocontrol. Adv Synth Catal 2008, 350, 411. <>
  • Leyva Antonio, Blum Francesca E., Hewitt Peter R., Ley Steven V.: Functionalised butanediacetal-protected 1,2-diols as suitable partners for Pd-catalysed cross-coupling reactions. Tetrahedron 2008, 64, 2348. <>
  • Mallyabaeva M. I., Spivak A. Yu., Tyumkina T. V., Knyshenko O. V., Odinokov V. N.: New method for the synthesis of (3R,7R)-hexahydrofarnesyl bromide based on the microwave-activated regioselective enolization of homochiral phytone. Russ Chem Bull 2007, 56, 2443. <>
  • Stuermer Rainer, Hauer Bernhard, Hall Melanie, Faber Kurt: Asymmetric bioreduction of activated C=C bonds using enoate reductases from the old yellow enzyme family. Curr Opin Chem Biol 2007, 11, 203. <>
  • Kumar Atul, Maurya Ram Awatar: Bakers’ yeast catalyzed synthesis of polyhydroquinoline derivatives via an unsymmetrical Hantzsch reaction. Tetrahetron Lett 2007, 48, 3887. <>
  • Kumar Atul, Maurya Ram Awatar: An efficient bakers’ yeast catalyzed synthesis of 3,4-dihydropyrimidin-2-(1H)-ones. Tetrahetron Lett 2007, 48, 4569. <>
  • Hall Mélanie, Hauer Bernhard, Stuermer Rainer, Kroutil Wolfgang, Faber Kurt: Asymmetric whole-cell bioreduction of an α,β-unsaturated aldehyde (citral): competing prim-alcohol dehydrogenase and C–C lyase activities. Tet Asymm 2006, 17, 3058. <>
  • Lee Jung Hwan: Synthesis of Hantsch 1,4-dihydropyridines by fermenting bakers’ yeast. Tetrahetron Lett 2005, 46, 7329. <>
  • Carballeira J.D, Valmaseda M, Alvarez E, Gago J.V.Sinisterra: Gongronella butleri, Schizosaccharomyces octosporus and Diplogelasinospora grovesii: novel microorganisms useful for the stereoselective reduction of ketones. Enzyme Microbiology Technology 2004, 34, 611. <>
  • Skip King G. G., Gries Regine, Gries Gerhard, Slessor K. N.: Optical isomers of 3,13-dimethylheptadecane: Sex pheromone components of the western false hemlock looper,Nepytia freemani (Lepidoptera: Geometridae). J Chem Ecol 1995, 21, 2027. <>
  • Fronza Giovanni, Fuganti Claudio, Grasselli Piero, Mele Andrea: On the asymmetric dihydroxylation of (2S,3R) 5-phenylpent-4-en-2,3-diol derivatives. Tetrahedron 1994, 50, 5021. <>