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Pure Appl. Chem., 1986, Vol. 58, No. 2, pp. 283-294

Biomimetic syntheses of aromatic polyketide metabolites

T. M. Harris and C. M. Harris

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  • Posehn Sarah E., Kim Sun Young, Wee Andrew G. H., Suh Dae-Yeon: Mapping the Mechanism of the Resorcinol Ring Formation Catalyzed by ArsB, a Type III Polyketide Synthase from Azotobacter vinelandii. ChemBioChem 2012, 13, 2212. <>
  • Ames Brian D., Lee Ming-Yue, Moody Colleen, Zhang Wenjun, Tang Yi, Tsai Shiou-Chuan: Structural and Biochemical Characterization of ZhuI Aromatase/Cyclase from the R1128 Polyketide Pathway. Biochemistry (Wash ) 2011, 50, 8392. <>
  • Evans Simon E., Williams Christopher, Arthur Christopher J., Płoskoń Eliza, Wattana-amorn Pakorn, Cox Russell J., Crosby John, Willis Christine L., Simpson Thomas J., Crump Matthew P.: Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). Journal of Molecular Biology 2009, 389, 511. <>
  • Shi She-Po, Morita Hiroyuki, Wanibuchi Kiyofumi, Noguchi Hiroshi, Abe Ikuro: Enzymatic formation of unnatural novel polyketide scaffolds by plant-specific type III polyketide synthase. Tetrahetron Lett 2009, 50, 2150. <>
  • Abe Ikuro: Engineering of Plant Polyketide Biosynthesis. Chem Pharm Bull 2008, 56, 1505. <>
  • Keatinge-Clay Adrian T, Maltby David A, Medzihradszky Katalin F, Khosla Chaitan, Stroud Robert M: An antibiotic factory caught in action. Nat Struct Mol Biol 2004, 11, 888. <>
  • Xiang L., Kalaitzis J. A., Moore B. S.: EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions. Proceedings of the National Academy of Sciences 2004, 101, 15609. <>
  • Xiang Longkuan, Kalaitzis John A., Nilsen George, Chen Li, Moore Bradley S.: Mutational Analysis of the Enterocin Favorskii Biosynthetic Rearrangement. Org Lett 2002, 4, 957. <>
  • Falk Heinz: Vom Photosensibilisator Hypericin zum Photorezeptor Stentorin – die Chemie der Phenanthroperylenchinone. Angew Chem 1999, 111, 3306. <<3306::AID-ANGE3306>3.0.CO;2-E>
  • Yamaguchi Toshio, Kurosaki Fumiya, Suh Dae-Yeon, Sankawa Ushio, Nishioka Mizue, Akiyama Takumi, Shibuya Masaaki, Ebizuka Yutaka: Cross-reaction of chalcone synthase and stilbene synthase overexpressed in Escherichia coli. FEBS Letters 1999, 460, 457. <>
  • Hutchinson C. R.: Microbial polyketide synthases: More and more prolific. Proceedings of the National Academy of Sciences 1999, 96, 3336. <>
  • Hutchinson C. Richard: Drug Synthesis by Genetically Engineered Microorganisms. Bio/Tech 1994, 12, 375. <>
  • Sherman David H, Bibb Maureen J, Simpson Thomas J, Johnson Darrin, Malpartida Francisco, Fernandez-Moreno Miguel, Martinez Eduardo, Hutchinson C.Richard, Hopwood David A: Molecular genetic analysis reveals a putative bifunctional polyketide cyclase/dehydrase gene from Streptomycea coelicolor and Streptomyces violoceoruber, and a cyclase/O-methyltransferase from Streptomyces glaucescens. Tetrahedron 1991, 47, 6029. <>
  • Sartori Giovanni, Casnati Giuseppe, Bigi Franca, Baraldi Davide: Friedel-crafts coordinated processes: Selective cyclooligomerization of acyl chlorides. Tetrahetron Lett 1991, 32, 2153. <>
  • Cervello Jordi, Marquet Jorge, Moreno-Mañas Marcial: Copper and cobalt mediated regioselective alkylation of polyketide models: methyl 3,5-dioxohexanoate and triacetic acid lactone. Tetrahedron 1990, 46, 2035. <>
  • Marquet Jorge, Moreno-Mañas Marcial, Prat María: Copper protection in the palladium catalyzed regioselective allylation of a model polyketide: Methyl 3,5-dioxohexanoate. Tetrahetron Lett 1989, 30, 3105. <>
  • Sato Tsuneo, Inoue Masami, Kobara Satoru, Otera Junzo, Nozaki Hitosi: Divergent synthesis of 1,3- and 1,4-diketones from β-methoxy-γ-phenylthio ketones accessible through novel phenylthio migration reaction. Tetrahetron Lett 1989, 30, 91. <>
  • Cervello Jordi, Marquet Jorge, Moreno-Mañas Marcial: Copper complex protection in the regioselective alkylation of methyl 3,5-dioxohexanoate. Preparation of 3-alkyl derivatives of 4-hydroxy-6-methyl-2-pyrone. Tetrahetron Lett 1987, 28, 3715. <>