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Pure Appl. Chem., 1977, Vol. 49, No. 9, pp. 1361-1384

http://dx.doi.org/10.1351/pac197749091361

Mutasynthesis of new antibiotics

K. L. Rinehart, Jr.

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  • Mancuso Lena, Jürjens Gerrit, Hermane Jekaterina, Harmrolfs Kirsten, Eichner Simone, Fohrer Jörg, Collisi Wera, Sasse Florenz, Kirschning Andreas: Bioreduction of Aryl Azides during Mutasynthesis of New Ansamitocins. Org. Lett. 2013, 15, 4442. <http://dx.doi.org/10.1021/ol401989e>
  • Knobloch Tobias, Harmrolfs Kirsten, Taft Florian, Thomaszewski Binia, Sasse Florenz, Kirschning Andreas: Mutational Biosynthesis of Ansamitocin Antibiotics: A Diversity-Oriented Approach to Exploit Biosynthetic Flexibility. Chem Eur J of Chem Bio 2011, 12, 540. <http://dx.doi.org/10.1002/cbic.201000608>
  • Shi Guanying, Zhang Xingang, Wu Lang, Xie Jin, Tao Ke, Hou Taiping: Mutational biosynthesis of neomycin analogs by a mutant of neomycin-producing Streptomyces fradiae . Folia Microbiology 2011, 56, 555. <http://dx.doi.org/10.1007/s12223-011-0082-5>
  • Mutanten können mehr. Nachr Chem 2010, 58, 23. <http://dx.doi.org/10.1002/nadc.201069169>
  • Taft Florian, Brünjes Marco, Floss Heinz G., Czempinski Nadine, Grond Stephanie, Sasse Florenz, Kirschning Andreas: Highly Active Ansamitocin Derivatives: Mutasynthesis Using an AHBA-Blocked Mutant. Chem Eur J of Chem Bio 2008, 9, 1057. <http://dx.doi.org/10.1002/cbic.200700742>
  • Kennedy Jonathan: Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products. Nat Prod Rep 2008, 25, 25. <http://dx.doi.org/10.1039/b707678a>
  • Nisbet Louis J.: Current strategies in the search for bioactive microbial metabolites. J Chem Technol Biotechnol 2007, 32, 251. <http://dx.doi.org/10.1002/jctb.5030320129>
  • Kirschning Andreas, Taft Florian, Knobloch Tobias: Total synthesis approaches to natural product derivatives based on the combination of chemical synthesis and metabolic engineering. Org Biomol Chem 2007, 5, 3245. <http://dx.doi.org/10.1039/b709549j>
  • Ziehl Martina, He Jing, Dahse Hans-Martin, Hertweck Christian: Mutasynthese von Aureonitril, einem Aureothin-Derivat mit signifikant verbesserter zytostatischer Aktivität. Angew Chem 2005, 117, 1226. <http://dx.doi.org/10.1002/ange.200461990>
  • Bode Helge B., Müller Rolf: Der Einfluss bakterieller Genomik auf die Naturstoff-Forschung. Angew Chem 2005, 117, 6988. <http://dx.doi.org/10.1002/ange.200501080>
  • Ziehl Martina, He Jing, Dahse Hans-Martin, Hertweck Christian: Mutasynthesis of Aureonitrile: An Aureothin Derivative with Significantly Improved Cytostatic Effect. Angew Chem Int Ed 2005, 44, 1202. <http://dx.doi.org/10.1002/anie.200461990>
  • Bode Helge B., Müller Rolf: The Impact of Bacterial Genomics on Natural Product Research. Angew Chem Int Ed 2005, 44, 6828. <http://dx.doi.org/10.1002/anie.200501080>
  • Weist S., Süssmuth R. D.: Mutational biosynthesis—a tool for the generation of structural diversity in the biosynthesis of antibiotics. Appl Microbiol Biotechnol 2005, 68, 141. <http://dx.doi.org/10.1007/s00253-005-1891-8>
  • Wohlleben Wolfgang, Pelzer Stefan: New Compounds By Combining “Modern” Genomics and “Old-Fashioned” Mutasynthesis. CHEM BIOL 2002, 9, 1163. <http://dx.doi.org/10.1016/S1074-5521(02)00267-3>
  • Hotta K, Okami Y: Diversity in aminoglycoside antibiotic resistance of actinomycetes and its exploitation in the search for novel antibiotics. J Ind Microbiol Biotech 1996, 17, 352. <http://dx.doi.org/10.1007/BF01574766>
  • Floss Heinz G., Strohl William R.: Genetic engineering of hybrid antibiotics - a progress report. Tetrahedron 1991, 47, 6045. <http://dx.doi.org/10.1016/S0040-4020(01)86495-4>
  • Richard Hutchinson C.: Prospects for the discovery of new (Hybrid) antibiotics by genetic engineering of antibiotic-producing bacteria. Med Res Rev 1988, 8, 557. <http://dx.doi.org/10.1002/med.2610080406>
  • Floss Heinz G.: Hybrid antibiotics — the contribution of the new gene combinations. Trends in Biotechnol 1987, 5, 111. <http://dx.doi.org/10.1016/0167-7799(87)90030-8>
  • Braun Heinz, Klier Konrad, Kresze Günter, Sabuni Mahmoud, Werbitzky Oleg, Winkler Johannes: Polyhydroxyamine via Diensynthese mit Nitrosoverbindungen, X.trans-5,6-Dimethoxy-1,3-cyclohexadien als Edukt bei der Synthese von Vorstufen optisch aktiver Streptamine. Liebigs Ann Chem 1986, 1986, 1360. <http://dx.doi.org/10.1002/jlac.198619860806>
  • Rinehart Kenneth L.: Newer Methods for Characterization of Antibiotics II. Antibiotic Structure Studied by Mass Spectrometry. Bio/Tech 1983, 1, 581. <http://dx.doi.org/10.1038/nbt0983-581>
  • Castellanos Lila, Cléophax Jeanine, Colas Claudine, Gero Stephan D., Leboul Jean, Mercier Daniel, Olesker Alain, Rolland Alain, Quiclet-Sire Béatrice, Sepulchre Anne-Marie: Synthesis of aminocyclitols from l-quinic acid. Carbohydrates Research 1980, 82, 283. <http://dx.doi.org/10.1016/S0008-6215(00)85704-3>