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Pure Appl. Chem., 2007, Vol. 79, No. 2, pp. 163-172

Recent results toward the stereoselective synthesis of biologically active natural products

Luiz C. Dias, Luciana G. de Oliveira and Paulo R. R. Meira

Instituto de Química, Universidade Estadual de Campinas, UNICAMP, C.P. 6154, CEP 13084-971, Campinas, São Paulo, Brazil

Abstract: This paper describes the convergent and stereocontrolled asymmetric total synthesis of (+)-crocacins C and D, potent inhibitors of animal cell cultures and several yeasts and fungi, and (-)-callystatin A, a potent antitumor polyketide.