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Pure Appl. Chem., 2007, Vol. 79, No. 12, pp. 2217-2227

http://dx.doi.org/10.1351/pac200779122217

H-Phosphonates: Versatile synthetic precursors to biologically active phosphorus compounds*

Adam Kraszewski1 and Jacek Stawinski1,2

1 Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznan, Poland
2 Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S-10691 Stockholm, Sweden

Abstract: In this review, a short account of H-phosphonate chemistry and its application to the synthesis of biologically important phosphates and their analogs is given.
*Invited contribution to a collection of papers for the IUPAC project 2005-042-1-300 "Chemistry for Biology". Other contributions to the project are published in this issue, pp. 2179-2366.

Keywords

biological activity; drugs; H-phosphonates; nucleic acids; phosphate analogs.

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References (94) Cited by 20 articles Other PAC articles by these authors