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Pure Appl. Chem., 2003, Vol. 75, No. 11-12, pp. 1733-1742

Biological function and mode of action of nuclear xenobiotic receptors

J. Sonoda and R. M. Evans

Howard Hughes Medical Institute, Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA

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  • Wallace Bret D., Betts Laurie, Talmage Garrick, Pollet Rebecca M., Holman Natalie S., Redinbo Matthew R.: Structural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXRα. Journal of Molecular Biology 2013, 425, 2561. <>
  • Wallace Bret D., Redinbo Matthew R.: Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective. Drug Metabolism Reviews 2013, 45, 79. <>
  • Li Tao, Yu Ruth T, Atkins Annette R, Downes Michael, Tukey Robert H, Evans Ronald M: Targeting the pregnane X receptor in liver injury. Expert Opin. Ther. Targets 2012, 16, 1075. <>
  • Fery Yvonne, Mueller Stefan O., Schrenk Dieter: Development of stably transfected human and rat hepatoma cell lines for the species-specific assessment of xenobiotic response enhancer module (XREM)-dependent induction of drug metabolism. Toxicol 2010, 277, 11. <>
  • Sonoda Junichiro, Pei Liming, Evans Ronald M.: Nuclear receptors: Decoding metabolic disease. FEBS Letters 2008, 582, 2. <>
  • Hernandez Juan P., Chapman Laura M., Kretschmer Xiomara C., Baldwin William S.: Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ mice. TOXICOL APPL PHARMAC 2006, 216, 186. <>